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Literature summary extracted from

  • Yamamoto, T.; Suzuki, N.
    Expression and function of cGMP-dependent protein kinase type I during medaka fish embryogenesis (2005), J. Biol. Chem., 280, 16979-16986.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.7.11.12 cGMP dependent on Oryzias latipes

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.11.12 DNA sequence determination and analysis, expression in NG108-15 hybrid cells constructed of mouseneuroblastoma cell line N18TG-2 and rat glioma cell line C6BU-1 Oryzias latipes

Protein Variants

EC Number Protein Variants Comment Organism
2.7.11.12 additional information injection of PKG-Ialpha-specific antisense or overexpression constructs into two-cell stage embryos causes severe abnormalities in the developing embryos, phenotypes, overview Oryzias latipes
2.7.11.12 additional information injection of PKG-Ibeta-specific antisense or overexpression constructs into two-cell stage embryos causes severe abnormalities in the developing embryos, phenotypes, overview Oryzias latipes

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.11.12 KT5823 PKG inhibitor; PKG inhibitor Oryzias latipes

Organism

EC Number Organism UniProt Comment Textmining
2.7.11.12 Oryzias latipes Q75PY3 PKG Ibeta; makada fish, enzyme form PKG I in two iszymes alpha and beta
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2.7.11.12 Oryzias latipes Q75PY4 PKG Ialpha; makada fish, enzyme form PKG I in two iszymes alpha and beta
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.11.12 auditory vesicle embryonal, high expression of isozyme PKGIbeta Oryzias latipes
-
2.7.11.12 embryo expression of both PKGIalpha and PKGIbeta after late gastrula stage Oryzias latipes
-
2.7.11.12 gill arch embryonal, high expression of isozyme PKGIalpha Oryzias latipes
-
2.7.11.12 spinal cord embryonal, high expression of isozyme PKGIalpha Oryzias latipes
-

Synonyms

EC Number Synonyms Comment Organism
2.7.11.12 PKG I
-
Oryzias latipes