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Literature summary extracted from

  • Ginger, M.L.; Ngazoa, E.S.; Pereira, C.A.; Pullen, T.J.; Kabiri, M.; Becker, K.; Gull, K.; Steverding, D.
    Intracellular positioning of isoforms explains an unusually large adenylate kinase gene family in the parasite Trypanosoma brucei (2005), J. Biol. Chem., 280, 11781-11789.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.4.3 expression in Escherichia coli Trypanosoma brucei

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.4.3 P1,P5-di(adenosine-5')pentaphosphate
-
 Trypanosoma brucei

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.7.4.3 0.00017
-
 CMP
-
 Trypanosoma brucei
2.7.4.3 0.00018
-
 ATP
-
 Trypanosoma brucei
2.7.4.3 0.0032
-
 AMP
-
 Trypanosoma brucei

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.4.3 glycosome adenylate kinase isoform D Trypanosoma brucei 20015
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.7.4.3 24000
-
 gel filtration Trypanosoma brucei

Organism

EC Number Organism UniProt Comment Textmining
2.7.4.3 Trypanosoma brucei
-
-
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.7.4.3 additional information
-
 Vmax 77 AMP/ATP Trypanosoma brucei
2.7.4.3 additional information
-
 Vmax 78 CMP/CTP Trypanosoma brucei

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.4.3 ATP + AMP adenylate kinase isoform G Trypanosoma brucei ADP + ADP
-
 ?
2.7.4.3 ATP + CMP adenylate kinase isoform G Trypanosoma brucei ADP + CDP
-
 ?
2.7.4.3 ATP + UMP adenylate kinase isoform G Trypanosoma brucei ADP + UDP
-
 ?
2.7.4.3 CTP + AMP adenylate kinase isoform G Trypanosoma brucei CDP + ADP
-
 ?
2.7.4.3 GTP + AMP adenylate kinase isoform G Trypanosoma brucei GDP + ADP
-
 ?
2.7.4.3 ITP + AMP adenylate kinase isoform G Trypanosoma brucei IDP + ADP
-
 ?
2.7.4.3 additional information ATP + IMP 0.1% activity, ATP + GMP 0.3% activity Trypanosoma brucei ?
-
 ?
2.7.4.3 UTP + AMP adenylate kinase isoform G Trypanosoma brucei UDP + ADP
-
 ?