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Literature summary extracted from

  • Major, L.L.; Wolucka, B.A.; Naismith, J.H.
    Structure and function of GDP-mannose-3',5'-epimerase: an enzyme which performs three chemical reactions at the same active site (2005), J. Am. Chem. Soc., 127, 18309-18320.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
5.1.3.18 expression in Escherichia coli Arabidopsis thaliana

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
5.1.3.18 sitting drop vapor diffusion method, structures of complexes of the enzyme with GDP-alpha-D-mannose, GDP-beta-L-galactose and a mixture of GDP-beta-L-gulose. Structure of native wild-type enzyme in complex with GDP-D-mannose, native GME K178R, SeMet GME K178E, native GME Y174F in complex with GDP-L-galactose and native GME K217A in complex with GDP-D-mannose Arabidopsis thaliana

Organism

EC Number Organism UniProt Comment Textmining
5.1.3.18 Arabidopsis thaliana
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.1.3.18 GDP-alpha-D-mannose
-
 Arabidopsis thaliana GDP-beta-L-galactose + GDP-beta-L-gulose
-
 ?

Synonyms

EC Number Synonyms Comment Organism
5.1.3.18 GDP-mannose-3',5'-epimerase
-
 Arabidopsis thaliana
5.1.3.18 GME
-
 Arabidopsis thaliana