EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.7.1.33 | (R)-3-azido-4,4-dimethyl-dihydro-furan-2-one | - |
Escherichia coli | |
2.7.1.33 | (R)-3-azido-4,4-dimethyl-dihydro-furan-2-one | - |
Staphylococcus aureus | |
2.7.1.33 | (R)-4-(2,4-dihydroxy-3,3-dimethyl-butyrylamino)-butyric acid | 80.6% inhibition at 0.1 mM, purified enzyme | Aspergillus nidulans | |
2.7.1.33 | (R)-4-(2,4-dihydroxy-3,3-dimethyl-butyrylamino)-butyric acid | 29.4% inhibition at 0.1 mM, purified enzyme | Escherichia coli | |
2.7.1.33 | (R)-4-(2,4-dihydroxy-3,3-dimethyl-butyrylamino)-butyric acid | 2.7% inhibition at 0.1 mM, cell extract | Mus musculus | |
2.7.1.33 | (R)-4-(2,4-dihydroxy-3,3-dimethyl-butyrylamino)-butyric acid | 78.7% inhibition at 0.1 mM, purified enzyme | Staphylococcus aureus | |
2.7.1.33 | (R)-4-(2-amino-4-hydroxy-3,3-dimethyl-butyrylamino)-butyric acid | 11% inhibition at 0.1 mM, purified enzyme | Escherichia coli | |
2.7.1.33 | (R)-4-(2-amino-4-hydroxy-3,3-dimethyl-butyrylamino)-butyric acid | 13.1% inhibition at 0.1 mM, cell extract | Mus musculus | |
2.7.1.33 | (R)-4-(2-azido-4-hydroxy-3,3-dimethyl-butyrylamino)-butyric acid | - |
Escherichia coli | |
2.7.1.33 | (R)-4-(2-azido-4-hydroxy-3,3-dimethyl-butyrylamino)-butyric acid | - |
Staphylococcus aureus | |
2.7.1.33 | (S)-4-(2,4-dihydroxy-3,3-dimethyl-butyrylamino)-butyric acid | 12.5% inhibition at 0.1 mM, purified enzyme | Escherichia coli | |
2.7.1.33 | (S)-4-(2,4-dihydroxy-3,3-dimethyl-butyrylamino)-butyric acid | 54.6% inhibition at 0.1 mM, purified enzyme | Staphylococcus aureus | |
2.7.1.33 | (S)-trifluoro-methanesulfonic acid 4,4-dimethyl-2-oxo-tetrahydro-furan-3-yl-ester | - |
Escherichia coli | |
2.7.1.33 | (S)-trifluoro-methanesulfonic acid 4,4-dimethyl-2-oxo-tetrahydro-furan-3-yl-ester | - |
Staphylococcus aureus | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-(2-heptylcarbamoyl-ethyl)-butyramide | 10.7% inhibition at 0.1 mM, purified enzyme | Aspergillus nidulans | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-(2-heptylcarbamoyl-ethyl)-butyramide | 76.4% inhibition at 0.1 mM, purified enzyme | Escherichia coli | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-(2-heptylcarbamoyl-ethyl)-butyramide | 89.6% inhibition at 0.1 mM, cell extract | Mus musculus | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-(2-heptylcarbamoyl-ethyl)-butyramide | 98.2% inhibition at 0.1 mM, purified enzyme | Staphylococcus aureus | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-(2-isobutylcarbamoyl-ethyl)-butyramide | 46.2% inhibition at 0.1 mM, purified enzyme | Aspergillus nidulans | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-(2-isobutylcarbamoyl-ethyl)-butyramide | 71.2% inhibition at 0.1 mM, purified enzyme | Escherichia coli | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-(2-isobutylcarbamoyl-ethyl)-butyramide | 89.9% inhibition at 0.1 mM, cell extract | Mus musculus | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-(2-isobutylcarbamoyl-ethyl)-butyramide | 97.1% inhibition at 0.1 mM, purified enzyme | Staphylococcus aureus | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-(2-pentylcarbamoyl-ethyl)-butyramide | 12.6% inhibition at 0.1 mM, purified enzyme | Aspergillus nidulans | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-(2-pentylcarbamoyl-ethyl)-butyramide | 72.2% inhibition at 0.1 mM, purified enzyme | Escherichia coli | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-(2-pentylcarbamoyl-ethyl)-butyramide | 81.4% inhibition at 0.1 mM, cell extract | Mus musculus | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-(2-pentylcarbamoyl-ethyl)-butyramide | 98.8% inhibition at 0.1 mM, purified enzyme | Staphylococcus aureus | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-(2-phenethylcarbamoyl-ethyl)-butyramide | 59.5% inhibition at 0.1 mM, purified enzyme | Aspergillus nidulans | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-(2-phenethylcarbamoyl-ethyl)-butyramide | 57.8% inhibition at 0.1 mM, purified enzyme | Escherichia coli | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-(2-phenethylcarbamoyl-ethyl)-butyramide | 80.9% inhibition at 0.1 mM, cell extract | Mus musculus | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-(2-phenethylcarbamoyl-ethyl)-butyramide | 89.5% inhibition at 0.1 mM, purified enzyme | Staphylococcus aureus | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-(2-propylcarbamoylethyl)-butyramide | 51.4% inhibition at 0.1 mM, purified enzyme | Aspergillus nidulans | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-(2-propylcarbamoylethyl)-butyramide | 82.5% inhibition at 0.1 mM, purified enzyme | Escherichia coli | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-(2-propylcarbamoylethyl)-butyramide | 86.8% inhibition at 0.1 mM, cell extract | Mus musculus | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-(2-propylcarbamoylethyl)-butyramide | 99.1% inhibition at 0.1 mM, purified enzyme | Staphylococcus aureus | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-(2-[1-methyl-3-phenyl-propylcarbamoyl]-ethyl)-butyramide | 40.7% inhibition at 0.1 mM, purified enzyme | Aspergillus nidulans | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-(2-[1-methyl-3-phenyl-propylcarbamoyl]-ethyl)-butyramide | 71.7% inhibition at 0.1 mM, purified enzyme | Escherichia coli | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-(2-[1-methyl-3-phenyl-propylcarbamoyl]-ethyl)-butyramide | 84.6% inhibition at 0.1 mM, cell extract | Mus musculus | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-(2-[1-methyl-3-phenyl-propylcarbamoyl]-ethyl)-butyramide | 86.4% inhibition at 0.1 mM, purified enzyme | Staphylococcus aureus | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-(2-[2-(3,4-dimethoxy-phenyl)-ethylcarbamoyl]-ethyl)-butyramide | 35.7% inhibition at 0.1 mM, purified enzyme | Aspergillus nidulans | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-(2-[2-(3,4-dimethoxy-phenyl)-ethylcarbamoyl]-ethyl)-butyramide | 44.2% inhibition at 0.1 mM, purified enzyme | Escherichia coli | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-(2-[2-(3,4-dimethoxy-phenyl)-ethylcarbamoyl]-ethyl)-butyramide | 70.5% inhibition at 0.1 mM, cell extract | Mus musculus | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-(2-[2-(3,4-dimethoxy-phenyl)-ethylcarbamoyl]-ethyl)-butyramide | 17.7% inhibition at 0.1 mM, purified enzyme | Staphylococcus aureus | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-(2-[3,4,5-trimethoxy-benzylcarbamoyl]-ethyl)-butyramide | 28.4% inhibition at 0.1 mM, purified enzyme | Aspergillus nidulans | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-(2-[3,4,5-trimethoxy-benzylcarbamoyl]-ethyl)-butyramide | 33.4% inhibition at 0.1 mM, purified enzyme | Escherichia coli | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-(2-[3,4,5-trimethoxy-benzylcarbamoyl]-ethyl)-butyramide | 57.4% inhibition at 0.1 mM, cell extract | Mus musculus | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-(2-[3,4,5-trimethoxy-benzylcarbamoyl]-ethyl)-butyramide | 8.7% inhibition at 0.1 mM, purified enzyme | Staphylococcus aureus | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-[2-(2,6,6-trimethylbicyclo[3.1.1]hept-3-ylcarbamoyl)-ethyl]-butyramide | 71.9% inhibition at 0.1 mM, purified enzyme | Aspergillus nidulans | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-[2-(2,6,6-trimethylbicyclo[3.1.1]hept-3-ylcarbamoyl)-ethyl]-butyramide | 3.0% inhibition at 0.1 mM, purified enzyme | Escherichia coli | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-[2-(2,6,6-trimethylbicyclo[3.1.1]hept-3-ylcarbamoyl)-ethyl]-butyramide | 93.3% inhibition at 0.1 mM, cell extract | Mus musculus | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-[2-(2,6,6-trimethylbicyclo[3.1.1]hept-3-ylcarbamoyl)-ethyl]-butyramide | 76.6% inhibition at 0.1 mM, purified enzyme | Staphylococcus aureus | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-[2-(2-ethoxy-ethylcarbamoyl)-ethyl]-butyramide | 41.8% inhibition at 0.1 mM, purified enzyme | Aspergillus nidulans | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-[2-(2-ethoxy-ethylcarbamoyl)-ethyl]-butyramide | 28.6% inhibition at 0.1 mM, purified enzyme | Escherichia coli | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-[2-(2-ethoxy-ethylcarbamoyl)-ethyl]-butyramide | 68.9% inhibition at 0.1 mM, cell extract | Mus musculus | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-[2-(2-ethoxy-ethylcarbamoyl)-ethyl]-butyramide | 95.1% inhibition at 0.1 mM, purified enzyme | Staphylococcus aureus | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-[2-(2-ethylsulfanylethylcarbamoyl)-ethyl]-butyramide | 61.0% inhibition at 0.1 mM, purified enzyme | Aspergillus nidulans | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-[2-(2-ethylsulfanylethylcarbamoyl)-ethyl]-butyramide | 53.7% inhibition at 0.1 mM, purified enzyme | Escherichia coli | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-[2-(2-ethylsulfanylethylcarbamoyl)-ethyl]-butyramide | 82.9% inhibition at 0.1 mM, cell extract | Mus musculus | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-[2-(2-ethylsulfanylethylcarbamoyl)-ethyl]-butyramide | 97.6% inhibition at 0.1 mM, purified enzyme | Staphylococcus aureus | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-[2-(2-methylsulfanylethylcarbamoyl)-ethyl]-butyramide | 49.7% inhibition at 0.1 mM, purified enzyme | Aspergillus nidulans | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-[2-(2-methylsulfanylethylcarbamoyl)-ethyl]-butyramide | 61.9% inhibition at 0.1 mM, purified enzyme | Escherichia coli | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-[2-(2-methylsulfanylethylcarbamoyl)-ethyl]-butyramide | 85.0% inhibition at 0.1 mM, cell extract | Mus musculus | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-[2-(2-methylsulfanylethylcarbamoyl)-ethyl]-butyramide | 96.5% inhibition at 0.1 mM, purified enzyme | Staphylococcus aureus | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-[2-(2-morpholin-4-yl-ethylcarbamoyl)-ethyl]-butyramide | 13.7% inhibition at 0.1 mM, purified enzyme | Aspergillus nidulans | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-[2-(2-morpholin-4-yl-ethylcarbamoyl)-ethyl]-butyramide | 10.7% inhibition at 0.1 mM, purified enzyme | Escherichia coli | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-[2-(2-morpholin-4-yl-ethylcarbamoyl)-ethyl]-butyramide | 39.1% inhibition at 0.1 mM, cell extract | Mus musculus | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-[2-(2-morpholin-4-yl-ethylcarbamoyl)-ethyl]-butyramide | 4.2% inhibition at 0.1 mM, purified enzyme | Staphylococcus aureus | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-[2-(3,7-dimethylocta-2,6-dienylcarbamoyl)-ethyl]-butyramide | 92.2% inhibition at 0.1 mM, purified enzyme | Aspergillus nidulans | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-[2-(3,7-dimethylocta-2,6-dienylcarbamoyl)-ethyl]-butyramide | 90.6% inhibition at 0.1 mM, purified enzyme | Escherichia coli | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-[2-(3,7-dimethylocta-2,6-dienylcarbamoyl)-ethyl]-butyramide | 98.9% inhibition at 0.1 mM, cell extract | Mus musculus | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-[2-(3,7-dimethylocta-2,6-dienylcarbamoyl)-ethyl]-butyramide | 97.2% inhibition at 0.1 mM, purified enzyme | Staphylococcus aureus | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-[2-(3-ethoxy-propylcarbamoyl)-ethyl]-butyramide | 62.1% inhibition at 0.1 mM, purified enzyme | Aspergillus nidulans | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-[2-(3-ethoxy-propylcarbamoyl)-ethyl]-butyramide | 32.3% inhibition at 0.1 mM, purified enzyme | Escherichia coli | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-[2-(3-ethoxy-propylcarbamoyl)-ethyl]-butyramide | 61.2% inhibition at 0.1 mM, cell extract | Mus musculus | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-[2-(3-ethoxy-propylcarbamoyl)-ethyl]-butyramide | 96.2% inhibition at 0.1 mM, purified enzyme | Staphylococcus aureus | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-[2-(3-methylsulfanylpropylcarbamoyl)-ethyl]-butyramide | 72.6% inhibition at 0.1 mM, purified enzyme | Aspergillus nidulans | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-[2-(3-methylsulfanylpropylcarbamoyl)-ethyl]-butyramide | 54.3% inhibition at 0.1 mM, purified enzyme | Escherichia coli | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-[2-(3-methylsulfanylpropylcarbamoyl)-ethyl]-butyramide | 87.2% inhibition at 0.1 mM, cell extract | Mus musculus | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-[2-(3-methylsulfanylpropylcarbamoyl)-ethyl]-butyramide | 97.7% inhibition at 0.1 mM, purified enzyme | Staphylococcus aureus | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-[2-(4-methoxy-benzylcarbamoyl)-ethyl]-3,3-dimethyl-butyramide | 54.7% inhibition at 0.1 mM, purified enzyme | Aspergillus nidulans | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-[2-(4-methoxy-benzylcarbamoyl)-ethyl]-3,3-dimethyl-butyramide | 55.7% inhibition at 0.1 mM, purified enzyme | Escherichia coli | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-[2-(4-methoxy-benzylcarbamoyl)-ethyl]-3,3-dimethyl-butyramide | 82.2% inhibition at 0.1 mM, cell extract | Mus musculus | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-[2-(4-methoxy-benzylcarbamoyl)-ethyl]-3,3-dimethyl-butyramide | 53.9% inhibition at 0.1 mM, purified enzyme | Staphylococcus aureus | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-[3-(4-benzyl-piperazin-1-yl)-3-oxo-propyl]-butyramide | 15.9% inhibition at 0.1 mM, purified enzyme | Aspergillus nidulans | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-[3-(4-benzyl-piperazin-1-yl)-3-oxo-propyl]-butyramide | 7.3% inhibition at 0.1 mM, purified enzyme | Escherichia coli | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-[3-(4-benzyl-piperazin-1-yl)-3-oxo-propyl]-butyramide | 73.0% inhibition at 0.1 mM, cell extract | Mus musculus | |
2.7.1.33 | 2,4-dihydroxy-3,3-dimethyl N-[3-(4-benzyl-piperazin-1-yl)-3-oxo-propyl]-butyramide | 9.3% inhibition at 0.1 mM, purified enzyme | Staphylococcus aureus | |
2.7.1.33 | 2,4-dihydroxy-N-[2-(2-hydroxy-ethylcarbamoyl)-ethyl]-3,3-dimethyl-butyramide | 25.9% inhibition at 0.1 mM, purified enzyme | Aspergillus nidulans | |
2.7.1.33 | 2,4-dihydroxy-N-[2-(2-hydroxy-ethylcarbamoyl)-ethyl]-3,3-dimethyl-butyramide | 3.4% inhibition at 0.1 mM, purified enzyme | Escherichia coli | |
2.7.1.33 | 2,4-dihydroxy-N-[2-(2-hydroxy-ethylcarbamoyl)-ethyl]-3,3-dimethyl-butyramide | 56.7% inhibition at 0.1 mM, cell extract | Mus musculus | |
2.7.1.33 | 2,4-dihydroxy-N-[2-(2-hydroxy-ethylcarbamoyl)-ethyl]-3,3-dimethyl-butyramide | 72.2% inhibition at 0.1 mM, purified enzyme | Staphylococcus aureus | |
2.7.1.33 | 2,4-dihydroxy-N-[2-(2-methoxy-ethylcarbamoyl)-ethyl]-3,3-dimethyl-butyramide | 26.8% inhibition at 0.1 mM, purified enzyme | Aspergillus nidulans | |
2.7.1.33 | 2,4-dihydroxy-N-[2-(2-methoxy-ethylcarbamoyl)-ethyl]-3,3-dimethyl-butyramide | 28.7% inhibition at 0.1 mM, purified enzyme | Escherichia coli | |
2.7.1.33 | 2,4-dihydroxy-N-[2-(2-methoxy-ethylcarbamoyl)-ethyl]-3,3-dimethyl-butyramide | 67.6% inhibition at 0.1 mM, cell extract | Mus musculus | |
2.7.1.33 | 2,4-dihydroxy-N-[2-(2-methoxy-ethylcarbamoyl)-ethyl]-3,3-dimethyl-butyramide | 90.1% inhibition at 0.1 mM, purified enzyme | Staphylococcus aureus | |
2.7.1.33 | 2,4-dihydroxy-N-[2-(3-hydroxy-propylcarbamoyl)-ethyl]-3,3-dimethyl-butyramide | i.e. pantothenol, 36.7% inhibition at 0.1 mM, purified enzyme | Aspergillus nidulans | |
2.7.1.33 | 2,4-dihydroxy-N-[2-(3-hydroxy-propylcarbamoyl)-ethyl]-3,3-dimethyl-butyramide | i.e. pantothenol, 11.5% inhibition at 0.1 mM, purified enzyme | Escherichia coli | |
2.7.1.33 | 2,4-dihydroxy-N-[2-(3-hydroxy-propylcarbamoyl)-ethyl]-3,3-dimethyl-butyramide | i.e. pantothenol, 70.3% inhibition at 0.1 mM, cell extract | Mus musculus | |
2.7.1.33 | 2,4-dihydroxy-N-[2-(3-hydroxy-propylcarbamoyl)-ethyl]-3,3-dimethyl-butyramide | i.e. pantothenol, 79.9% inhibition at 0.1 mM, purified enzyme | Staphylococcus aureus | |
2.7.1.33 | 2,4-dihydroxy-N-[2-(3-methoxy-propylcarbamoyl)-ethyl]-3,3-dimethyl-butyramide | 52.9% inhibition at 0.1 mM, purified enzyme | Aspergillus nidulans | |
2.7.1.33 | 2,4-dihydroxy-N-[2-(3-methoxy-propylcarbamoyl)-ethyl]-3,3-dimethyl-butyramide | 38.6% inhibition at 0.1 mM, purified enzyme | Escherichia coli | |
2.7.1.33 | 2,4-dihydroxy-N-[2-(3-methoxy-propylcarbamoyl)-ethyl]-3,3-dimethyl-butyramide | 64.9% inhibition at 0.1 mM, cell extract | Mus musculus | |
2.7.1.33 | 2,4-dihydroxy-N-[2-(3-methoxy-propylcarbamoyl)-ethyl]-3,3-dimethyl-butyramide | 94.4% inhibition at 0.1 mM, purified enzyme | Staphylococcus aureus | |
2.7.1.33 | additional information | no inhibition by (R)-4-(2-amino-4-hydroxy-3,3-dimethyl-butyrylamino)-butyric acid and (S)-4-(2,4-dihydroxy-3,3-dimethyl-butyrylamino)-butyric acid, structural features required for enzyme inhibition, overview | Aspergillus nidulans | |
2.7.1.33 | additional information | structural features required for enzyme inhibition, overview | Escherichia coli | |
2.7.1.33 | additional information | no inhibition by (S)-4-(2,4-dihydroxy-3,3-dimethyl-butyrylamino)-butyric acid, structural features required for enzyme inhibition, overview | Mus musculus | |
2.7.1.33 | additional information | no inhibition by (R)-4-(2-amino-4-hydroxy-3,3-dimethyl-butyrylamino)-butyric acid, structural features required for enzyme inhibition, overview | Staphylococcus aureus | |
2.7.1.33 | N-heptylpantothenamide | - |
Aspergillus nidulans | |
2.7.1.33 | N-pentylpantothenamide | - |
Aspergillus nidulans |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
2.7.1.33 | Mg2+ | - |
Staphylococcus aureus | |
2.7.1.33 | Mg2+ | - |
Mus musculus | |
2.7.1.33 | Mg2+ | - |
Escherichia coli | |
2.7.1.33 | Mg2+ | - |
Aspergillus nidulans |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.1.33 | ATP + (R)-pantothenate | Staphylococcus aureus | first step in coenzyme A biosynthesis | ADP + (R)-4'-phosphopantothenate | - |
? | |
2.7.1.33 | ATP + (R)-pantothenate | Mus musculus | first step in coenzyme A biosynthesis | ADP + (R)-4'-phosphopantothenate | - |
? | |
2.7.1.33 | ATP + (R)-pantothenate | Escherichia coli | first step in coenzyme A biosynthesis | ADP + (R)-4'-phosphopantothenate | - |
? | |
2.7.1.33 | ATP + (R)-pantothenate | Aspergillus nidulans | first step in coenzyme A biosynthesis | ADP + (R)-4'-phosphopantothenate | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.1.33 | Aspergillus nidulans | - |
- |
- |
2.7.1.33 | Escherichia coli | - |
- |
- |
2.7.1.33 | Mus musculus | - |
isozyme PanK1alpha | - |
2.7.1.33 | Staphylococcus aureus | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.1.33 | ATP + (R)-pantothenate | - |
Staphylococcus aureus | ADP + (R)-4'-phosphopantothenate | - |
? | |
2.7.1.33 | ATP + (R)-pantothenate | - |
Mus musculus | ADP + (R)-4'-phosphopantothenate | - |
? | |
2.7.1.33 | ATP + (R)-pantothenate | - |
Escherichia coli | ADP + (R)-4'-phosphopantothenate | - |
? | |
2.7.1.33 | ATP + (R)-pantothenate | - |
Aspergillus nidulans | ADP + (R)-4'-phosphopantothenate | - |
? | |
2.7.1.33 | ATP + (R)-pantothenate | first step in coenzyme A biosynthesis | Staphylococcus aureus | ADP + (R)-4'-phosphopantothenate | - |
? | |
2.7.1.33 | ATP + (R)-pantothenate | first step in coenzyme A biosynthesis | Mus musculus | ADP + (R)-4'-phosphopantothenate | - |
? | |
2.7.1.33 | ATP + (R)-pantothenate | first step in coenzyme A biosynthesis | Escherichia coli | ADP + (R)-4'-phosphopantothenate | - |
? | |
2.7.1.33 | ATP + (R)-pantothenate | first step in coenzyme A biosynthesis | Aspergillus nidulans | ADP + (R)-4'-phosphopantothenate | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.7.1.33 | PanK | - |
Staphylococcus aureus |
2.7.1.33 | PanK | - |
Mus musculus |
2.7.1.33 | PanK | - |
Escherichia coli |
2.7.1.33 | PanK | - |
Aspergillus nidulans |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
2.7.1.33 | 37 | - |
assay at | Staphylococcus aureus |
2.7.1.33 | 37 | - |
assay at | Mus musculus |
2.7.1.33 | 37 | - |
assay at | Escherichia coli |
2.7.1.33 | 37 | - |
assay at | Aspergillus nidulans |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
2.7.1.33 | 7.5 | - |
assay at | Staphylococcus aureus |
2.7.1.33 | 7.5 | - |
assay at | Mus musculus |
2.7.1.33 | 7.5 | - |
assay at | Escherichia coli |
2.7.1.33 | 7.5 | - |
assay at | Aspergillus nidulans |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
2.7.1.33 | ATP | - |
Staphylococcus aureus | |
2.7.1.33 | ATP | - |
Mus musculus | |
2.7.1.33 | ATP | - |
Escherichia coli | |
2.7.1.33 | ATP | - |
Aspergillus nidulans |