EC Number | Application | Comment | Organism |
---|---|---|---|
5.4.99.7 | medicine | S23515 can exert hypolipidemic effects in addition to its hypotensive activities | Homo sapiens |
5.4.99.7 | medicine | S23515 can exert hypolipidemic effects in addition to its hypotensive activities | Rattus norvegicus |
5.4.99.7 | medicine | S23515 can exert hypolipidemic effects in addition to its hypotensive activities | Macaca fascicularis |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
5.4.99.7 | BIBB 515 | - |
Homo sapiens | |
5.4.99.7 | BIBB 515 | - |
Macaca fascicularis | |
5.4.99.7 | BIBB 515 | - |
Rattus norvegicus | |
5.4.99.7 | S23515 | - |
Homo sapiens | |
5.4.99.7 | S23515 | - |
Macaca fascicularis | |
5.4.99.7 | S23515 | - |
Rattus norvegicus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
5.4.99.7 | 2,3-monoepoxysqualene | Homo sapiens | - |
lanosterol | - |
? | |
5.4.99.7 | 2,3-monoepoxysqualene | Rattus norvegicus | - |
lanosterol | - |
? | |
5.4.99.7 | 2,3-monoepoxysqualene | Macaca fascicularis | - |
lanosterol | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
5.4.99.7 | Homo sapiens | - |
- |
- |
5.4.99.7 | Macaca fascicularis | - |
Cynomolgus | - |
5.4.99.7 | Rattus norvegicus | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
5.4.99.7 | Hep-G2 cell | - |
Homo sapiens | - |
5.4.99.7 | hepatocyte | primary hepatocyte | Homo sapiens | - |
5.4.99.7 | hepatocyte | primary hepatocyte | Rattus norvegicus | - |
5.4.99.7 | hepatocyte | primary hepatocyte | Macaca fascicularis | - |
5.4.99.7 | THP-1 cell | - |
Homo sapiens | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
5.4.99.7 | 2,3-monoepoxysqualene | - |
Homo sapiens | lanosterol | - |
? | |
5.4.99.7 | 2,3-monoepoxysqualene | - |
Rattus norvegicus | lanosterol | - |
? | |
5.4.99.7 | 2,3-monoepoxysqualene | - |
Macaca fascicularis | lanosterol | - |
? | |
5.4.99.7 | 2,3:22,23-diepoxysqualene | - |
Homo sapiens | 24(S),25-epoxylanosterol | - |
? | |
5.4.99.7 | 2,3:22,23-diepoxysqualene | - |
Rattus norvegicus | 24(S),25-epoxylanosterol | - |
? | |
5.4.99.7 | 2,3:22,23-diepoxysqualene | - |
Macaca fascicularis | 24(S),25-epoxylanosterol | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
5.4.99.7 | OSC | - |
Homo sapiens |
5.4.99.7 | OSC | - |
Rattus norvegicus |
5.4.99.7 | OSC | - |
Macaca fascicularis |
5.4.99.7 | oxidosqualene:lanosterol cyclase | - |
Homo sapiens |
5.4.99.7 | oxidosqualene:lanosterol cyclase | - |
Rattus norvegicus |
5.4.99.7 | oxidosqualene:lanosterol cyclase | - |
Macaca fascicularis |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
5.4.99.7 | 0.008 | - |
S23515 | - |
Rattus norvegicus |