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Literature summary extracted from

  • Bleijerveld, O.B.; Klein, W.; Vaandrager, A.B.; Helms, J.B.; Houweling, M.
    Control of the CDPethanolamine pathway in mammalian cells: effect of CTP:phosphoethanolamine cytidylyltransferase overexpression and the amount of intracellular diacylglycerol (2004), Biochem. J., 379, 711-719.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.7.14 cDNA encoding CTP:phosphoethanolamine cytidylyltransferase is transiently or stably transfected in CHO cells and a rat liver-derived cell line (McA-RH7777), resulting in a maximum of 26fold and 4fold increase in specific activity of CTP:phosphoethanolamine cytidylyltransferase respectively Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.7.14 CTP + ethanolamine phosphate Rattus norvegicus at physiological ethanolamine concentrations, the supply of CDPethanolamine, via the expression level of CTP:phosphoethanolamine cytidylyltransferase, together with the amount of cellular diacylglycerol available to CTP:phosphoethanolamine cytidylyltransferase are major factors regulating the flux through the CDPethanolamine pathway diphosphate + CDP-ethanolamine
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Organism

EC Number Organism UniProt Comment Textmining
2.7.7.14 Rattus norvegicus
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Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.7.14 liver
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 Rattus norvegicus
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.7.14 CTP + ethanolamine phosphate at physiological ethanolamine concentrations, the supply of CDPethanolamine, via the expression level of CTP:phosphoethanolamine cytidylyltransferase, together with the amount of cellular diacylglycerol available to CTP:phosphoethanolamine cytidylyltransferase are major factors regulating the flux through the CDPethanolamine pathway Rattus norvegicus diphosphate + CDP-ethanolamine
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Synonyms

EC Number Synonyms Comment Organism
2.7.7.14 CTP:phosphoethanolamine cytidylyltransferase
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 Rattus norvegicus