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Literature summary extracted from

  • Yanase, M.; Ikeda, H.; Ogata, I.; Matsui, A.; Noiri, E.; Tomiya, T.; Arai, M.; Inoue, Y.; Tejima, K.; Nagashima, K.; Nishikawa, T.; Shibata, M.; Ikebe, M.; Rojkind, M.; Fujiwara, K.
    Functional diversity between Rho-kinase- and MLCK-mediated cytoskeletal actions in a myofibroblast-like hepatic stellate cell line (2003), Biochem. Biophys. Res. Commun., 305, 223-228.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.11.18 ML-7 calmodulin/enzyme-specific inhibitor, inhibits cell attachment to extracellular substrate in vivo, attenuates the activation of GTP-binding protein Rac and cell migration Rattus norvegicus
2.7.11.18 W-7 calmodulin/enzyme-specific inhibitor, attenuates cell migration in vivo Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining

Organism

EC Number Organism UniProt Comment Textmining
2.7.11.18 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.11.18 Kupffer cell myofibroblast-like stellate cell line, previously called Ito cells, lipocytes, or fat-storing cells Rattus norvegicus
-

Synonyms

EC Number Synonyms Comment Organism
2.7.11.18 MLCK
-
 Rattus norvegicus

Cofactor

EC Number Cofactor Comment Organism Structure
2.7.11.18 ATP
-
 Rattus norvegicus
2.7.11.18 Calmodulin
-
 Rattus norvegicus