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Literature summary extracted from

  • Lee, P.C.; Mijts, B.N.; Petri, R.; Watts, K.T.; Schmidt-Dannert, C.
    Alteration of product specificity of Aeropyrum pernix farnesylgeranyl diphosphate synthase (Fgs) by directed evolution (2004), Protein Eng. Des. Sel., 17, 771-777.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.5.1.81 expression of wild-type and mutant enzymes in Escherichia coli Aeropyrum pernix

Protein Variants

EC Number Protein Variants Comment Organism
2.5.1.81 additional information directed evolution is used to create mutant FGPP synthases that confirm the importance of amino acids upstream of the FARM of prenyl diphosphate synthases and demonstrate the significance of mutations upstream of an additional conserved region (141GQ142). Product chain-length distribution can be also controlled by a structural change provoked by a cooperative interaction of amino acids Aeropyrum pernix

Organism

EC Number Organism UniProt Comment Textmining
2.5.1.81 Aeropyrum pernix Q9UWR6
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-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.5.1.81
-
 Aeropyrum pernix

Synonyms

EC Number Synonyms Comment Organism
2.5.1.81 C25 FGPP synthase
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 Aeropyrum pernix
2.5.1.81 farnesylgeranyl diphosphate synthase
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-
2.5.1.81 Fgs
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 Aeropyrum pernix