EC Number | Cloned (Comment) | Organism |
---|---|---|
2.4.1.222 | gene fng, DNA and amino acid sequence determination and analysis | Drosophila melanogaster |
EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
2.4.1.222 | D327N | EMS mutagenesis, transheterozygote, mutation on allele 14, lethal phenotype | Drosophila melanogaster |
2.4.1.222 | E220K | EMS mutagenesis, transheterozygote, mutation on allele 3, lethal phenotype | Drosophila melanogaster |
2.4.1.222 | G295D | EMS mutagenesis, transheterozygote, mutation on allele L81, lethal phenotype | Drosophila melanogaster |
2.4.1.222 | K196E | EMS mutagenesis, transheterozygote, mutation on allele 11, lethal phenotype | Drosophila melanogaster |
2.4.1.222 | K196N | EMS mutagenesis, transheterozygote, mutation on allele 11, lethal phenotype | Drosophila melanogaster |
2.4.1.222 | L213F | EMS mutagenesis, transheterozygote, mutation on allele L83, lethal phenotype | Drosophila melanogaster |
2.4.1.222 | L398Q | EMS mutagenesis, transheterozygote, mutation on allele 2, phenotype overview | Drosophila melanogaster |
2.4.1.222 | additional information | construction and genetic analysis of mutated alleles, several mutants with introduced stop codons, mutant phenotypes analysis, mutants show altered wing vein numbers and structure, overview | Drosophila melanogaster |
2.4.1.222 | S350T | EMS mutagenesis, transheterozygote, mutation on allele 1, lethal phenotype | Drosophila melanogaster |
2.4.1.222 | T184M | EMS mutagenesis, transheterozygote, phenotype overview | Drosophila melanogaster |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.4.1.222 | Notch + UDP-D-GlcNAc | Drosophila melanogaster | enzyme modulates signaling through Notch receptors by modifying O-linked fucose on epidermal growth factor-like domains | beta-D-glucosaminyl-Notch + UDP | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.4.1.222 | Drosophila melanogaster | Q24324 | - |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.4.1.222 | Notch + UDP-D-GlcNAc | enzyme modulates signaling through Notch receptors by modifying O-linked fucose on epidermal growth factor-like domains | Drosophila melanogaster | beta-D-glucosaminyl-Notch + UDP | - |
? | |
2.4.1.222 | Notch + UDP-D-GlcNAc | Notch protein is O-fucosylated at a serine or threonine residue in the epidermal growth factor-like domain | Drosophila melanogaster | beta-D-glucosaminyl-Notch + UDP | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.4.1.222 | beta1,3-N-acetylglucosaminyltransferase | - |
Drosophila melanogaster |
2.4.1.222 | FNG | - |
Drosophila melanogaster |
2.4.1.222 | Fringe protein | - |
Drosophila melanogaster |