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Literature summary extracted from

  • Zarnowski, T.; Rejdak, R.; Zagorski, Z.; Juenemann, A.G.; Zrenner, E.; Kocki, T.; Urbanska, E.M.; Turski, W.A.
    Content of kynurenic acid and activity of kynurenine aminotransferases in mammalian eyes (2004), Ophthalmic Res., 36, 124-128.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.6.1.7 L-tryptophan 1 mM, isoform KAT I, 3% residual activity, isoform KAT II, 129% activity Bos taurus
2.6.1.7 Quisqualic acid 1 mM, isoform KAT I, 81% residual activity, isoform KAT II, 1% residual activity Bos taurus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.6.1.7 additional information
-
 additional information isoform KAT I, vitreous body, 0.25 pM/g wet tissue/hour, retina, 1.65, isoform KAT II, vitreous body, 0.25 pM/g wet tissue/hour, retina 2.37 Oryctolagus cuniculus
2.6.1.7 additional information
-
 additional information isoform KAT I, vitreous body, 0.57 pM/g wet tissue/hour, retina, 3.42, isoform KAT II, vitreous body, 2.56 pM/g wet tissue/hour, retina 10.75 Homo sapiens
2.6.1.7 additional information
-
 additional information isoform KAT I, vitreous body, 0.82 pM/g wet tissue/hour, retina, 0.39, isoform KAT II, vitreous body, 1.05 pM/g wet tissue/hour, retina 1.88 Bos taurus

Organism

EC Number Organism UniProt Comment Textmining
2.6.1.7 Bos taurus
-
-
-
2.6.1.7 Homo sapiens
-
-
-
2.6.1.7 Oryctolagus cuniculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.6.1.7 eye vitreous body and retina Homo sapiens
-
2.6.1.7 eye vitreous body and retina Bos taurus
-
2.6.1.7 eye vitreous body and retina Oryctolagus cuniculus
-