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Literature summary extracted from

  • Zhang, S.; Cai, M.; Zhang, S.W.; Hu, Y.; Gu, J.X.
    Involvement of beta 1,4 galactosyltransferase I and Gal beta1-4GlcNAc groups in human hepatocarcinoma cell apoptosis (2003), Mol. Cell. Biochem., 243, 81-86.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.4.1.90 transient functional overexpression in 7721 hepatocarcinoma cells Homo sapiens

Protein Variants

EC Number Protein Variants Comment Organism
2.4.1.90 additional information the enzyme transfected 7721 hepatocarcinoma cell line is more susceptible to cycloheximide-induced apoptosis than the wild-type cells, cells show increased enzyme activity and expression of Galbeta1,4GlcNAc groups on the cell surface Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.4.1.90 UDP-galactose + N-acetyl-D-glucosamine Homo sapiens synthesis of Galbeta1,4GlcNAc groups in N-linked sugar chains of glycoproteins involved in many physiological functions, e.g. sperm-egg interactions, cell migration, and embryonic development, enzyme expression is highly increased during cycloheximide-induced cell apoptosis in liver carcinoma UDP + N-acetyllactosamine
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.90 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.90 UDP-galactose + N-acetyl-D-glucosamine
-
 Homo sapiens UDP + N-acetyllactosamine
-
 ?
2.4.1.90 UDP-galactose + N-acetyl-D-glucosamine synthesis of Galbeta1,4GlcNAc groups in N-linked sugar chains of glycoproteins involved in many physiological functions, e.g. sperm-egg interactions, cell migration, and embryonic development, enzyme expression is highly increased during cycloheximide-induced cell apoptosis in liver carcinoma Homo sapiens UDP + N-acetyllactosamine
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.4.1.90 beta 1,4 galactosyltransferase I
-
 Homo sapiens
2.4.1.90 beta 1,4GTI
-
 Homo sapiens