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Literature summary extracted from

  • Diesel, B.; Seifert, M.; Radermacher, J.; Fischer, U.; Tilgen, W.; Reichrath, J.; Meese, E.
    Towards a complete picture of splice variants of the gene for 25-hydroxyvitamin D3 1alpha-hydroxylase in brain and skin cancer (2004), J. Steroid Biochem. Mol. Biol., 89-90, 527-532.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.15.18 25-hydroxyvitamin D3 + NADPH + O2 Homo sapiens final step of the activation of vitamin D 1alpha,25-dihydroxyvitamin D3 + NADP+ + H2O
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 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.15.18 Homo sapiens
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 several splicing variants
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Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.15.18 cervix carcinoma cell
-
 Homo sapiens
-
1.14.15.18 glioblastoma multiforme cell
-
 Homo sapiens
-
1.14.15.18 glioma cell
-
 Homo sapiens
-
1.14.15.18 kidney
-
 Homo sapiens
-
1.14.15.18 melanoma cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.15.18 25-hydroxyvitamin D3 + NADPH + O2
-
 Homo sapiens 1alpha,25-dihydroxyvitamin D3 + NADP+ + H2O
-
 ?
1.14.15.18 25-hydroxyvitamin D3 + NADPH + O2 final step of the activation of vitamin D Homo sapiens 1alpha,25-dihydroxyvitamin D3 + NADP+ + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.15.18 P450 cytochrome 25-hydroxyvitamin D3 1alpha-hydroxylase
-
 Homo sapiens