Literature summary extracted from

Inoue, Y.; Yu, A.M.; Yim, S.H.; Ma, X.; Krausz, K.W.; Inoue, J.; Xiang, C.C.; Brownstein, M.J.; Eggertsen, G.; Bjorkhem, I.; Gonzalez, F.J.
Regulation of bile acid biosynthesis by hepatocyte nuclear factor 4alpha (2006), J. Lipid Res., 47, 215-227.

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
1.14.14.139	additional information	Mus musculus	HNF4alpha directly binds to the promoter region of the mouse cyp8b1 and positively regulates its expression. CYP8B1 enzyme activity is absent in HNF4alphaDELTAL mice	?	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.14.14.139	Mus musculus	-	CYP8B1 enzyme activity is absent in HNF4alphaDELTAL mice	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.14.14.139	additional information	HNF4alpha directly binds to the promoter region of the mouse cyp8b1 and positively regulates its expression. CYP8B1 enzyme activity is absent in HNF4alphaDELTAL mice	Mus musculus	?	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
1.14.14.139	CYP8B1	-	Mus musculus

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Release 2023.1 (January 2023)