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Literature summary extracted from

  • Ford, L.T.; Berg, J.D.
    Determination of thiopurine S-methyltransferase activity in erythrocytes using 6-thioguanine as substrate and a non-extraction liquid chromatographic technique (2003), J. Chromatogr. B, 798, 111-115.
    View publication on PubMed

Application

EC Number Application Comment Organism
2.1.1.67 analysis determination of thiopurine S-methyltransferase activity in erythrocytes using 6-thioguanine as substrate and a non-extraction liquid chromatographic technique. This method minimzes sample-handling, reduces inherent imprecision, the possibility of laboratory error and with the potential for further automation, makes it ideal for use in a regional refferal laboratory Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.1.1.67 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.1.1.67 erythrocyte
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.1.1.67 additional information
-
 determination of thiopurine S-methyltransferase activity in erythrocytes using 6-thioguanine as substrate and a non-extraction liquid chromatographic technique. This method minimzes sample-handling, reduces inherent imprecision, the possibility of laboratory error and has a potential for further automation Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.1.67 S-adenosyl-L-methionine + 6-thioguanine
-
 Homo sapiens S-adenosyl-L-homocysteine + 6-methylthioguanine
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.1.1.67 TPMT
-
 Homo sapiens