Literature summary extracted from
Umland, T.C.; Wolff, E.C.; Park, M.H.; Davies, D.R.
A new crystal structure of deoxyhypusine synthase reveals the configuration of the active enzyme and of an enzyme-NAD-inhibitor ternary complex (2004), J. Biol. Chem., 279, 28697-28705.
Crystallization (Commentary)
EC Number |
Crystallization (Comment) |
Organism |
---|
2.5.1.46 |
at 2.2 A a new form II crystal of the deoxyhypusine synthase:NAD holoenzyme is grown at low ionic strength and pH 8.0, near the optimal pH for enzymatic activity |
Homo sapiens |
Inhibitors
EC Number |
Inhibitors |
Comment |
Organism |
Structure |
---|
2.5.1.46 |
N1-guanyl-1,7-diaminoheptane |
competitive |
Homo sapiens |
|
Organism
EC Number |
Organism |
UniProt |
Comment |
Textmining |
---|
2.5.1.46 |
Homo sapiens |
P49366 |
recombinant enzyme |
- |
Synonyms
EC Number |
Synonyms |
Comment |
Organism |
---|
2.5.1.46 |
DHS |
- |
Homo sapiens |