Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Umland, T.C.; Wolff, E.C.; Park, M.H.; Davies, D.R.
    A new crystal structure of deoxyhypusine synthase reveals the configuration of the active enzyme and of an enzyme-NAD-inhibitor ternary complex (2004), J. Biol. Chem., 279, 28697-28705.
    View publication on PubMed

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
2.5.1.46 at 2.2 A a new form II crystal of the deoxyhypusine synthase:NAD holoenzyme is grown at low ionic strength and pH 8.0, near the optimal pH for enzymatic activity Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.5.1.46 N1-guanyl-1,7-diaminoheptane competitive Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.5.1.46 Homo sapiens P49366 recombinant enzyme
-

Synonyms

EC Number Synonyms Comment Organism
2.5.1.46 DHS
-
Homo sapiens