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Literature summary extracted from

  • Tikellis, C.; Johnston, C.I.; Forbes, J.M.; Burns, W.C.; Burrell, L.M.; Risvanis, J.; Cooper, M.E.
    Characterization of renal angiotensin-converting enzyme 2 in diabetic nephropathy (2003), Hypertension, 41, 392-397.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.17.23 additional information rampiril does not influence the mRNA content in renal tubules Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.17.23 angiotensin I + H2O Rattus norvegicus
-
 angiotensin-(1-9) + Leu
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.17.23 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.17.23 kidney diabetic rats, 50% reduced enzyme content in renal tubules Rattus norvegicus
-
3.4.17.23 renal tubule predominantly in proximal tubules, diabetic rats, 30% reduced enzyme content Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.17.23 angiotensin I + H2O
-
 Rattus norvegicus angiotensin-(1-9) + Leu
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.17.23 ACE2
-
 Rattus norvegicus