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Literature summary extracted from

  • Tamburro, A.; Robuffo, I.; Heipieper, H.J.; Allocati, N.; Rotilio, D.; Di Ilio, C.; Favaloro, B.
    Expression of glutathione S-transferase and peptide methionine sulphoxide reductase in Ochrobactrum anthropi is correlated to the production of reactive oxygen species caused by aromatic substrates (2004), FEMS Microbiol. Lett., 241, 151-156.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.8.4.11 additional information enzyme expression is induced, together with the glutathione S-transferase, by toxic concentrations of aromatic substrates such as phenol and 4-chlorophenol which cause production of reactive oxygen species Brucella anthropi

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.8.4.11 cell envelope associated Brucella anthropi 30313
-
1.8.4.11 cytoplasmic membrane inner or outer side Brucella anthropi
-
-
1.8.4.11 additional information subcellular distribution of the enzyme in cells grown on 4-chlorophenol Brucella anthropi
-
-
1.8.4.11 periplasmic space
-
Brucella anthropi 42597
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.8.4.11 additional information Brucella anthropi detoxification enzyme ?
-
?
1.8.4.11 protein-L-methionine (S)-sulfoxide + thioredoxin Brucella anthropi enzyme provides protection against oxidative damage by reactive oxygen species and has a repair function for oxidized protein methionine residues protein-L-methionine + thioredoxin disulfide + H2O
-
?

Organism

EC Number Organism UniProt Comment Textmining
1.8.4.11 Brucella anthropi
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.8.4.11 culture condition:4-chlorophenol-grown cell
-
Brucella anthropi
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.8.4.11 additional information detoxification enzyme Brucella anthropi ?
-
?
1.8.4.11 protein-L-methionine (S)-sulfoxide + thioredoxin
-
Brucella anthropi protein-L-methionine + thioredoxin disulfide + H2O
-
?
1.8.4.11 protein-L-methionine (S)-sulfoxide + thioredoxin enzyme provides protection against oxidative damage by reactive oxygen species and has a repair function for oxidized protein methionine residues Brucella anthropi protein-L-methionine + thioredoxin disulfide + H2O
-
?

Synonyms

EC Number Synonyms Comment Organism
1.8.4.11 MsrA
-
Brucella anthropi
1.8.4.11 peptide methionine sulphoxide reductase
-
Brucella anthropi