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Literature summary extracted from

  • Andreesen, J.R.
    Glycine reductase mechanism (2004), Curr. Opin. Chem. Biol., 8, 454-461.
    View publication on PubMed

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.21.4.2 40000
-
 protein C, x * 40000 + x * 54000 Acetoanaerobium sticklandii
1.21.4.2 40000
-
 protein C, x * 40000 + x * 54000 Treponema denticola
1.21.4.2 40000
-
 protein C, x * 40000 + x * 54000 Tissierella creatinophila
1.21.4.2 54000
-
 protein C, x * 40000 + x * 54000 Acetoanaerobium sticklandii
1.21.4.2 54000
-
 protein C, x * 40000 + x * 54000 Treponema denticola
1.21.4.2 54000
-
 protein C, x * 40000 + x * 54000 Tissierella creatinophila
1.21.4.2 200000 240000 protein C, gel filtration Acetoanaerobium sticklandii
1.21.4.2 200000 240000 protein C, gel filtration Treponema denticola
1.21.4.2 200000 240000 protein C, gel filtration Tissierella creatinophila

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.21.4.2 glycine + phosphate + thioredoxin Acetoanaerobium sticklandii conservation of energy as acetyl phosphate acetyl phosphate + NH3 + thioredoxin disulfide + H2O
-
 ?
1.21.4.2 glycine + phosphate + thioredoxin Treponema denticola conservation of energy as acetyl phosphate acetyl phosphate + NH3 + thioredoxin disulfide + H2O
-
 ?
1.21.4.2 glycine + phosphate + thioredoxin Peptoclostridium acidaminophilum conservation of energy as acetyl phosphate acetyl phosphate + NH3 + thioredoxin disulfide + H2O
-
 ?
1.21.4.2 glycine + phosphate + thioredoxin Tissierella creatinophila conservation of energy as acetyl phosphate acetyl phosphate + NH3 + thioredoxin disulfide + H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.21.4.2 Acetoanaerobium sticklandii
-
 three protein system consisting of proteins A,B, and C
-
1.21.4.2 Peptoclostridium acidaminophilum
-
 three protein system consisting of proteins A,B, and C
-
1.21.4.2 Tissierella creatinophila
-
 three protein system consisting of proteins A,B, and C
-
1.21.4.2 Treponema denticola
-
 three protein system consisting of proteins A,B, and C
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.21.4.2 glycine + phosphate + thioredoxin
-
 Acetoanaerobium sticklandii acetyl phosphate + NH3 + thioredoxin disulfide + H2O
-
 ?
1.21.4.2 glycine + phosphate + thioredoxin
-
 Treponema denticola acetyl phosphate + NH3 + thioredoxin disulfide + H2O
-
 ?
1.21.4.2 glycine + phosphate + thioredoxin
-
 Peptoclostridium acidaminophilum acetyl phosphate + NH3 + thioredoxin disulfide + H2O
-
 ?
1.21.4.2 glycine + phosphate + thioredoxin
-
 Tissierella creatinophila acetyl phosphate + NH3 + thioredoxin disulfide + H2O
-
 ?
1.21.4.2 glycine + phosphate + thioredoxin conservation of energy as acetyl phosphate Acetoanaerobium sticklandii acetyl phosphate + NH3 + thioredoxin disulfide + H2O
-
 ?
1.21.4.2 glycine + phosphate + thioredoxin conservation of energy as acetyl phosphate Treponema denticola acetyl phosphate + NH3 + thioredoxin disulfide + H2O
-
 ?
1.21.4.2 glycine + phosphate + thioredoxin conservation of energy as acetyl phosphate Peptoclostridium acidaminophilum acetyl phosphate + NH3 + thioredoxin disulfide + H2O
-
 ?
1.21.4.2 glycine + phosphate + thioredoxin conservation of energy as acetyl phosphate Tissierella creatinophila acetyl phosphate + NH3 + thioredoxin disulfide + H2O
-
 ?

Subunits

EC Number Subunits Comment Organism
1.21.4.2 More three protein system consisting of protein A (17000 Da), protein B (47000 Da or 48000 Da, later processed into two proteins of 22000 and 25000 Da), and protein C (40000 or 54000 Da) Acetoanaerobium sticklandii
1.21.4.2 More three protein system consisting of protein A (17000 Da), protein B (47000 Da or 48000 Da, later processed into two proteins of 22000 and 25000 Da), and protein C (40000 or 54000 Da) Treponema denticola
1.21.4.2 More three protein system consisting of protein A (17000 Da), protein B (47000 Da or 48000 Da, later processed into two proteins of 22000 and 25000 Da), and protein C (40000 or 54000 Da) Peptoclostridium acidaminophilum
1.21.4.2 More three protein system consisting of protein A (17000 Da), protein B (47000 Da or 48000 Da, later processed into two proteins of 22000 and 25000 Da), and protein C (40000 or 54000 Da) Tissierella creatinophila
1.21.4.2 multimer protein C, x * 40000 + x * 54000 Acetoanaerobium sticklandii
1.21.4.2 multimer protein C, x * 40000 + x * 54000 Treponema denticola
1.21.4.2 multimer protein C, x * 40000 + x * 54000 Tissierella creatinophila