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Literature summary extracted from

  • Chandok, M.R.; Ytterberg, A.J.; van Wijk, K.J.; Klessig, D.F.
    The pathogen-inducible nitric oxide synthase (iNOS) in plants is a variant of the P protein of the glycine decarboxylase complex (2003), Cell, 113, 469-482.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.14.13.39 Calmodulin required Nicotiana tabacum

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.14.13.39 aminoguanidine
-
 Nicotiana tabacum
1.14.13.39 Ngamma,Ngamma-dimethyl-L-arginine
-
 Nicotiana tabacum

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.14.13.39 0.000383
-
 NADPH pH 7.0, 37°C Nicotiana tabacum
1.14.13.39 0.00746
-
 L-arginine pH 7.0, 37°C Nicotiana tabacum

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.14.13.39 Ca2+ required Nicotiana tabacum

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.14.13.39 115000
-
 x * 120000 + x * 115000, SDS-PAGE Nicotiana tabacum
1.14.13.39 120000
-
 x * 120000 + x * 115000, SDS-PAGE Nicotiana tabacum

Organism

EC Number Organism UniProt Comment Textmining
1.14.13.39 Nicotiana tabacum
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.13.39 leaf leaf extract Nicotiana tabacum
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.14.13.39 983.7
-
 pH 7.0, 37°C Nicotiana tabacum

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.13.39 2 L-arginine + 3 NADPH + 4 O2 + 3 H+
-
 Nicotiana tabacum 2 L-citrulline + 2 NO + 3 NADP+ + 4 H2O
-
 ?

Subunits

EC Number Subunits Comment Organism
1.14.13.39 ? x * 120000 + x * 115000, SDS-PAGE Nicotiana tabacum

Synonyms

EC Number Synonyms Comment Organism
1.14.13.39 iNOS
-
 Nicotiana tabacum

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.13.39 5,6,7,8-tetrahydro-L-biopterin
-
 Nicotiana tabacum
1.14.13.39 FAD
-
 Nicotiana tabacum
1.14.13.39 NADPH
-
 Nicotiana tabacum

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
1.14.13.39 0.00667
-
 Ngamma,Ngamma-dimethyl-L-arginine pH 7.0, 37°C Nicotiana tabacum