EC Number | Crystallization (Comment) | Organism |
---|---|---|
1.13.11.27 | crystal structure at 2.4 A resolution | Pseudomonas fluorescens |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
1.13.11.27 | Fe2+ | required for activity, the active-site iron is in the ferric oxidation state and coordinated by the side chains of two histidines and on glutamate | Pseudomonas fluorescens |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.13.11.27 | 4-hydroxyphenylpyruvate + O2 | Pseudomonas fluorescens | - |
homogentisate + CO2 | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.13.11.27 | Pseudomonas fluorescens | - |
- |
- |
EC Number | Reaction | Comment | Organism | Reaction ID |
---|---|---|---|---|
1.13.11.27 | 4-hydroxyphenylpyruvate + O2 = homogentisate + CO2 | ternary enzyme-substrate complex is firstly decarboxylated to the iron(II)-peracid intermediate followed by heterolytic cleavage of the O-O bond yielding an iron(IV)-oxospecies. This attacks the aromatic ring in C1 position. The arene oxide has no catalytic relevance | Pseudomonas fluorescens |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.13.11.27 | 4-hydroxyphenylpyruvate + O2 | - |
Pseudomonas fluorescens | homogentisate + CO2 | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.13.11.27 | 4-HPPD | - |
Pseudomonas fluorescens |