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Literature summary extracted from

  • Lian, W.; Gu, Y.; Pedersen, B.; Kukar, T.; Govindasamy, L.; Agbandje-McKenna, M.; Jin, S.; McKenna, R.; Wu, D.
    Crystallization and preliminary X-ray crystallographic studies on recombinant rat choline acetyltransferase (2004), Acta Crystallogr. Sect. D, 60, 374-375.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.3.1.6 expressed in Escherichia coli B834 Rattus norvegicus

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
2.3.1.6 hanging drop vapor diffusion method Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.6 membrane
-
 Rattus norvegicus 16020
-
2.3.1.6 soluble 80-90% of total activity Rattus norvegicus
-
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.6 acetyl-CoA + choline Rattus norvegicus synthesis of the neurotransmitter acetylcholine acetylcholine + CoA
-
 r

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.6 Rattus norvegicus
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
2.3.1.6 phosphoprotein phosphorylation enables membrane association Rattus norvegicus

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.1.6 recombinant enzyme using His-tag Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.6 neuron cholinergic neurons Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.6 acetyl-CoA + choline
-
 Rattus norvegicus acetylcholine + CoA
-
 r
2.3.1.6 acetyl-CoA + choline synthesis of the neurotransmitter acetylcholine Rattus norvegicus acetylcholine + CoA
-
 r

Subunits

EC Number Subunits Comment Organism
2.3.1.6 monomer crystal structure analysis Rattus norvegicus