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Literature summary extracted from

  • Nakagawasai, O.; Arai, Y.; Satoh, S.e.; Satoh, N.; Neda, M.; Hozumi, M.; Oka, R.; Hiraga, H.; Tadano, T.
    Monoamine oxidase and head-twitch response in mice. Mechanisms of alpha-methylated substrate derivatives (2004), Neurotoxicology, 25, 223-232.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.4.3.4 5-fluoro-alpha-methyltryptamine a drug causing head-twitch response, IC50: 0.00018 mM Mus musculus
1.4.3.4 5-fluorotryptamine a drug causing head-twitch response, IC50: 0.00018 mM Mus musculus
1.4.3.4 6-fluoro-alpha-methyltryptamine a drug causing head-twitch response, IC50: 0.00018 mM Mus musculus
1.4.3.4 6-fluorotryptamine a drug causing head-twitch response, IC50: 0.00018 mM Mus musculus

Organism

EC Number Organism UniProt Comment Textmining
1.4.3.4 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.4.3.4 forebrain
-
 Mus musculus
-

Synonyms

EC Number Synonyms Comment Organism
1.4.3.4 MAO-A
-
 Mus musculus
1.4.3.4 monoamine oxidase A
-
 Mus musculus

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
1.4.3.4 0.000032
-
 5-fluoro-alpha-methyltryptamine
-
 Mus musculus
1.4.3.4 0.0016
-
 6-fluoro-alpha-methyltryptamine
-
 Mus musculus

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
1.4.3.4 0.00018
-
 a drug causing head-twitch response, IC50: 0.00018 mM Mus musculus 5-fluorotryptamine
1.4.3.4 0.00018
-
 a drug causing head-twitch response, IC50: 0.00018 mM Mus musculus 6-fluorotryptamine
1.4.3.4 0.00018
-
 a drug causing head-twitch response, IC50: 0.00018 mM Mus musculus 5-fluoro-alpha-methyltryptamine
1.4.3.4 0.00018
-
 a drug causing head-twitch response, IC50: 0.00018 mM Mus musculus 6-fluoro-alpha-methyltryptamine