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Literature summary extracted from

  • Meador, M.G.; Rajagopalan, L.; Lloyd, R.S.; Dodson, M.L.
    Role of His-16 in turnover of T4 pyrimidine dimer glycosylase (2004), J. Biol. Chem., 279, 3348-3353.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.2.2.17 expression in Escherichia coli of several mutants Escherichia coli

Protein Variants

EC Number Protein Variants Comment Organism
3.2.2.17 H16A performs most functions tested in vivo, although at reduced rates compared with the wild type protein Escherichia coli
3.2.2.17 H16A decrease in enzymic activity, analysis of initial velocity Tequatrovirus T4
3.2.2.17 H16C performs most functions tested in vivo, although at reduced rates compared with the wild type protein Escherichia coli
3.2.2.17 H16C decrease in enzymic activity, analysis of initial velocity Tequatrovirus T4
3.2.2.17 H16D performs most functions tested in vivo, although at reduced rates compared with the wild type protein Escherichia coli
3.2.2.17 H16D decrease in enzymic activity, analysis of initial velocity Tequatrovirus T4
3.2.2.17 H16E performs most functions tested in vivo, although at reduced rates compared with the wild type protein Escherichia coli
3.2.2.17 H16E decrease in enzymic activity, analysis of initial velocity Tequatrovirus T4
3.2.2.17 H16K performs most functions tested in vivo, although at reduced rates compared with the wild type protein Escherichia coli
3.2.2.17 H16K decrease in enzymic activity, analysis of initial velocity Tequatrovirus T4
3.2.2.17 H16S performs most functions tested in vivo, although at reduced rates compared with the wild type protein Escherichia coli
3.2.2.17 H16S decrease in enzymic activity, analysis of initial velocity Tequatrovirus T4

Organism

EC Number Organism UniProt Comment Textmining
3.2.2.17 Escherichia coli
-
-
-
3.2.2.17 Tequatrovirus T4
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.2.2.17 to homogeneity, using several chromatographic steps Escherichia coli

Reaction

EC Number Reaction Comment Organism Reaction ID
3.2.2.17 thymidine-dimer-containing DNA + H2O = thymidine-dimer-containing DNA with apyrimidinic site scheme of reaction mechanism Tequatrovirus T4
a

Synonyms

EC Number Synonyms Comment Organism
3.2.2.17 pyrimidine dimer glycosylase
-
 Tequatrovirus T4
3.2.2.17 T4-PDG
-
 Tequatrovirus T4