EC Number | Cloned (Comment) | Organism |
---|---|---|
7.6.2.1 | LdMT is cloned by rescuing the resistance phenotype of the M-40 R cell line overexpression in Leishmania tarentolae | Leishmania donovani |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
7.6.2.1 | plasma membrane | - |
Leishmania donovani | 5886 | - |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
7.6.2.1 | additional information | Leishmania donovani | the enzyme is directly involved in miltefosine uptake in eukaryotic cells | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
7.6.2.1 | Leishmania donovani | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
7.6.2.1 | additional information | the enzyme is directly involved in miltefosine uptake in eukaryotic cells | Leishmania donovani | ? | - |
? | |
7.6.2.1 | additional information | the enzyme is able to promote the translocalisation of aminophospholipids and glycerophosphocholine molecules such as NBD-phosphatidylcholine and edelfosine and non glycerol based alkylphosphocholine miltefosin | Leishmania donovani | ? | - |
? |