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Literature summary extracted from

  • Peer, C.W.; Painter, M.H.; Rasche, M.E.; Ferry, J.G.
    Characterization of a CO:heterodisulfide oxidoreductase system from acetate-grown Methanosarcina thermophila (1994), J. Bacteriol., 176, 6974-6979.
    View publication on PubMedView publication on EuropePMC

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.8.98.1 soluble
-
 Methanosarcina thermophila
-
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.8.98.1 N-(7-[(2-sulfoethyl)dithio]heptanoyl)-3-O-phospho-L-threonine + reduced cytochrome b Methanosarcina thermophila electron transfer by a CO dehydrogenase in complex with the heterodisulfide oxidoreductase, no H2 uptake in vivo, reaction is part of the overall reduction of acetate to methane and H2O, also providing a proton-translocation redox system to drive ATP formation coenzyme B + coenzyme M + oxidized cytochrome b
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.8.98.1 Methanosarcina thermophila
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-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.8.98.1 culture condition:acetate-grown cell
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 Methanosarcina thermophila
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.8.98.1 N-(7-[(2-sulfoethyl)dithio]heptanoyl)-3-O-phospho-L-threonine + reduced cytochrome b
-
 Methanosarcina thermophila coenzyme B + coenzyme M + oxidized cytochrome b
-
 ?
1.8.98.1 N-(7-[(2-sulfoethyl)dithio]heptanoyl)-3-O-phospho-L-threonine + reduced cytochrome b electron transfer by a CO dehydrogenase in complex with the heterodisulfide oxidoreductase, no H2 uptake in vivo, reaction is part of the overall reduction of acetate to methane and H2O, also providing a proton-translocation redox system to drive ATP formation Methanosarcina thermophila coenzyme B + coenzyme M + oxidized cytochrome b
-
 ?
1.8.98.1 N-(7-[(2-sulfoethyl)dithio]heptanoyl)-3-O-phospho-L-threonine + reduced methylviologen
-
 Methanosarcina thermophila coenzyme B + coenzyme M + oxidized methylviologen
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.8.98.1 Co:CoM-S-S-CoB oxidoreductase system
-
 Methanosarcina thermophila
1.8.98.1 CO:heterodisulfide oxidoreductase system
-
 Methanosarcina thermophila

Cofactor

EC Number Cofactor Comment Organism Structure
1.8.98.1 additional information coenzyme F420 is not required Methanosarcina thermophila