EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
3.1.26.4 | KCl | activates | Escherichia coli | |
3.1.26.4 | KCl | activates | Homo sapiens | |
3.1.26.4 | Mg2+ | required | Escherichia coli | |
3.1.26.4 | Mg2+ | required | Homo sapiens |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.26.4 | RNA*DNA hybrid + H2O | Escherichia coli | cleaves the RNA portion | ? | - |
? | |
3.1.26.4 | RNA*DNA hybrid + H2O | Homo sapiens | cleaves the RNA portion | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.1.26.4 | Escherichia coli | - |
type 1 enzyme | - |
3.1.26.4 | Homo sapiens | - |
type 2 enzyme | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.26.4 | additional information | substrate characterization and substrate specificity | Homo sapiens | ? | - |
? | |
3.1.26.4 | additional information | substrate characterizationa and substrate specificity | Escherichia coli | ? | - |
? | |
3.1.26.4 | RNA*2'F-ANA-DNA hybrid + H2O | cleaves the RNA portion of hybrid duplexes of butyl-modified 2'F-ANA-DNA oligonucleotides containing acyclic interresidue units with complementary RNA | Escherichia coli | ? | - |
? | |
3.1.26.4 | RNA*2'F-ANA-DNA hybrid + H2O | cleaves the RNA portion of hybrid duplexes of butyl-modified 2'F-ANA-DNA oligonucleotides containing acyclic interresidue units with complementary RNA | Homo sapiens | ? | - |
? | |
3.1.26.4 | RNA*antisense-DNA hybrid + H2O | cleaves the RNA portion of hybrid duplexes of modified antisense DNA oligonucleotides containing acyclic interresidue units with complementary RNA | Escherichia coli | ? | - |
? | |
3.1.26.4 | RNA*antisense-DNA hybrid + H2O | cleaves the RNA portion of hybrid duplexes of modified antisense DNA oligonucleotides containing acyclic interresidue units with complementary RNA | Homo sapiens | ? | - |
? | |
3.1.26.4 | RNA*DNA hybrid + H2O | cleaves the RNA portion | Escherichia coli | ? | - |
? | |
3.1.26.4 | RNA*DNA hybrid + H2O | cleaves the RNA portion | Homo sapiens | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.1.26.4 | RNase HI | - |
Escherichia coli |
3.1.26.4 | RNase HII | - |
Homo sapiens |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
3.1.26.4 | 22 | - |
about, assay at room temperature | Escherichia coli |
3.1.26.4 | 22 | - |
about, assay at room temperature | Homo sapiens |
EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.1.26.4 | additional information | - |
additional information | - |
Escherichia coli | |
3.1.26.4 | additional information | - |
additional information | - |
Homo sapiens |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
3.1.26.4 | 7.8 | - |
assay at | Escherichia coli |
3.1.26.4 | 7.8 | - |
assay at | Homo sapiens |