EC Number | Cloned (Comment) | Organism |
---|---|---|
1.8.1.14 | - |
Pyrococcus horikoshii |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.8.1.14 | Pyrococcus horikoshii | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
1.8.1.14 | recombinant enzyme | Pyrococcus horikoshii |
EC Number | Reaction | Comment | Organism | Reaction ID |
---|---|---|---|---|
1.8.1.14 | 2 CoA + NADP+ = CoA-disulfide + NADPH + H+ | mechanism | Pyrococcus horikoshii |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.8.1.14 | CoA-disulfide + NAD(P)H + H+ | specific substrate | Pyrococcus horikoshii | CoA + NAD(P)+ | - |
? | |
1.8.1.14 | additional information | both NADPH and NADH are used efficiently, preference for NADPH with Km-value about eightfold lower than for NADH, no substrate: dephospho-CoA | Pyrococcus horikoshii | ? | - |
? |
EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.8.1.14 | 7.2 | - |
NADPH | 75°C | Pyrococcus horikoshii |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.8.1.14 | NADH | both NADPH and NADH are used efficiently, preference for NADPH with Km-value about eightfold lower than for NADH | Pyrococcus horikoshii | |
1.8.1.14 | NADPH | both NADPH and NADH are used efficiently, preference for NADPH with Km-value about eightfold lower than for NADH | Pyrococcus horikoshii |