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Literature summary extracted from
- Comparative characterization of bovine testicular hyaluronidase and a hyaluronate lyase from Streptococcus agalactiae in pharmaceutical preparations (2003), Eur. J. Pharm. Sci., 18, 267-277.
Application
| EC Number | Application | Comment | Organism |
|---|---|---|---|
| 4.2.2.1 | pharmacology | enzyme can be used for production of pharmaceuticals as an alternative to bovine testicular hyaluronidase, BTH, because the production of BTH is stopped due to risk of BSE | Streptococcus agalactiae |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 4.2.2.1 | 85000 | - |
x * 100000, SDS-PAGE, x * 85000, SDS-PAGE, x * 75000-50000, trypsin digested enzyme, SDS-PAGE | Streptococcus agalactiae |
| 4.2.2.1 | 100000 | - |
x * 100000, SDS-PAGE, x * 85000, SDS-PAGE, x * 75000-50000, trypsin digested enzyme, SDS-PAGE | Streptococcus agalactiae |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.2.2.1 | Streptococcus agalactiae | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 4.2.2.1 | additional information | - |
activity in pharmaceutical preparations | Streptococcus agalactiae |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.2.2.1 | hyaluronan | - |
Streptococcus agalactiae | 3-(4-deoxy-beta-D-gluc-4-enuronosyl)-N-acetyl-D-glucosamine | - |
? |  |
| 4.2.2.1 | additional information | fragments from trypsin digestion are still active, enzyme is active in SDS-PAGE | Streptococcus agalactiae | ? | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 4.2.2.1 | ? | x * 100000, SDS-PAGE, x * 85000, SDS-PAGE, x * 75000-50000, trypsin digested enzyme, SDS-PAGE | Streptococcus agalactiae |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 4.2.2.1 | More | from commercial pharmaceutical preparations Neopermease and Hylase Dessau | Streptococcus agalactiae |
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Release 2023.1 (January 2023)
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