Literature summary extracted from

Arribas, J.C.; Herrero, A.G.; Martin-Lomas, M.; Canada, F.J.; He, S.; Withers, S.G.
Differential mechanism-based labeling and unequivocal activity assignment of the two active sites of intestinal lactase/phlorizin hydrolase (2000), Eur. J. Biochem., 267, 6996-7005.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
3.2.1.62	2',4'-dinitrophenyl-2-deoxy-2-fluoro-beta-D-galactopyranoside	inactivation of lactase hydrolase activity	Ovis aries
3.2.1.62	2',4'-dinitrophenyl-2-deoxy-2-fluoro-beta-D-glucopyranoside	inactivation of phlorizin hydrolase activity	Ovis aries
3.2.1.62	D-galactal	inactivation of lactase hydrolase activity	Ovis aries
3.2.1.62	D-glucal	inactivation of lactase hydrolase activity	Ovis aries

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.2.1.62	Ovis aries	-	lamb, bifunctional lactase/phlorizin hydrolase complex	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining

Subunits

EC Number	Subunits	Comment	Organism
3.2.1.62	More	phlorizin hydrolysis occurs at region III of enzyme, lactase hydrolysis occurs at region IV	Ovis aries

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Release 2023.1 (January 2023)