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Literature summary extracted from

  • Alba-Lois, L.; Segal, C.; Rodarte, B.; Valdes-Lopez, V.; DeLuna, A.; Cardenas, R.
    NADP-glutamate dehydrogenase activity is increased under hyperosmotic conditions in the halotolerant yeast Debaryomyces hansenii (2004), Curr. Microbiol., 48, 68-72.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.4.1.4 KCl 500 mM, 80-90% inhibition, by high ionic strength Debaryomyces hansenii
1.4.1.4 NaCl 50 mM, 50% inhibition. 100 mM, about 60% inhibition. 500 mM, about 90% inhibition by high ionic strength Debaryomyces hansenii

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.4.1.4 0.021
-
 NADPH pH 8.0, 25°C Debaryomyces hansenii
1.4.1.4 2.2
-
 2-oxoglutarate pH 8.0, 25°C Debaryomyces hansenii
1.4.1.4 16
-
 NH3 pH 8.0, 25°C Debaryomyces hansenii

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.4.1.4 additional information Debaryomyces hansenii enzyme synthesis is increased under hyperosmotic conditions in the halotolerant yeast ?
-
 ?
1.4.1.4 additional information Debaryomyces hansenii Y7426 enzyme synthesis is increased under hyperosmotic conditions in the halotolerant yeast ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.4.1.4 Debaryomyces hansenii
-
-
-
1.4.1.4 Debaryomyces hansenii Y7426
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.4.1.4 2-oxoglutarate + NADPH + NH3
-
 Debaryomyces hansenii L-glutamate + NADP+ + H2O
-
 ?
1.4.1.4 2-oxoglutarate + NADPH + NH3
-
 Debaryomyces hansenii Y7426 L-glutamate + NADP+ + H2O
-
 ?
1.4.1.4 additional information enzyme synthesis is increased under hyperosmotic conditions in the halotolerant yeast Debaryomyces hansenii ?
-
 ?
1.4.1.4 additional information enzyme synthesis is increased under hyperosmotic conditions in the halotolerant yeast Debaryomyces hansenii Y7426 ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.4.1.4 NADP-GDH
-
 Debaryomyces hansenii
1.4.1.4 NADP-glutamate dehydrogenase
-
 Debaryomyces hansenii

Cofactor

EC Number Cofactor Comment Organism Structure
1.4.1.4 NADPH
-
 Debaryomyces hansenii