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Literature summary extracted from

  • Denicola, A.; Rubbo, H.; Haden, L.; Turrens, J.F.
    Extramitochondrial localization of NADH-fumarate reductase in trypanosomatids (2002), Comp. Biochem. Physiol. B, 133, 23-27.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.3.1.6 additional information extramitochondrial subcellular localization Trypanosoma brucei
-
-
1.3.1.6 additional information extramitochondrial subcellular localization Leishmania donovani
-
-
1.3.1.6 additional information extramitochondrial subcellular localization Trypanosoma cruzi
-
-

Organism

EC Number Organism UniProt Comment Textmining
1.3.1.6 Leishmania donovani
-
-
-
1.3.1.6 Leishmania donovani S-2
-
-
-
1.3.1.6 Trypanosoma brucei
-
-
-
1.3.1.6 Trypanosoma cruzi
-
 strains Y and Tulahuen
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.3.1.6 partial, release from subcellular compartment by treatment with digitonin Trypanosoma brucei
1.3.1.6 partial, release from subcellular compartment by treatment with digitonin Leishmania donovani
1.3.1.6 partial, release from subcellular compartment by treatment with digitonin Trypanosoma cruzi

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.3.1.6 epimastigote
-
 Trypanosoma cruzi
-
1.3.1.6 promastigote
-
 Leishmania donovani
-
1.3.1.6 trypomastigote procyclic Trypanosoma brucei
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.3.1.6 0.015
-
 epimastigote homogenate, strain Y Trypanosoma cruzi
1.3.1.6 0.017
-
 epimastigote homogenate, strain Y Trypanosoma cruzi
1.3.1.6 0.017
-
 promastigote homogenate Leishmania donovani
1.3.1.6 0.082
-
 procyclic trypomastigote homogenate, strain S-2 Trypanosoma brucei

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.3.1.6 fumarate + NADH + H+
-
 Trypanosoma brucei succinate + NAD+
-
 ?
1.3.1.6 fumarate + NADH + H+
-
 Leishmania donovani succinate + NAD+
-
 ?
1.3.1.6 fumarate + NADH + H+
-
 Trypanosoma cruzi succinate + NAD+
-
 ?
1.3.1.6 fumarate + NADH + H+
-
 Leishmania donovani S-2 succinate + NAD+
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.3.1.6 NADH-fumarate reductase
-
 Trypanosoma brucei
1.3.1.6 NADH-fumarate reductase
-
 Leishmania donovani
1.3.1.6 NADH-fumarate reductase
-
 Trypanosoma cruzi

Cofactor

EC Number Cofactor Comment Organism Structure
1.3.1.6 NADH
-
 Trypanosoma brucei
1.3.1.6 NADH
-
 Leishmania donovani
1.3.1.6 NADH
-
 Trypanosoma cruzi