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Literature summary extracted from

  • Houston, B.; Stewart, A.J.; Farquharson, C.
    PHOSPHO1-a novel phosphatase specifically expressed at sites of mineralisation in bone and cartilage (2004), Bone, 34, 629-637.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.1.3.75 from growth plate chondrocytes, expression in Escherichia coli TOP10 Gallus gallus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.1.3.75 28600
-
 x * 33000, recombinant PHOSPHO1, SDS-PAGE, x * 28600, x * 30400, alternative transcripts for PHOSPHO1 in growth cartilage, Western blot analysis Gallus gallus
3.1.3.75 30400
-
 x * 33000, recombinant PHOSPHO1, SDS-PAGE, x * 28600, x * 30400, alternative transcripts for PHOSPHO1 in growth cartilage, Western blot analysis Gallus gallus
3.1.3.75 33000
-
 x * 33000, recombinant PHOSPHO1, SDS-PAGE, x * 28600, x * 30400, alternative transcripts for PHOSPHO1 in growth cartilage, Western blot analysis Gallus gallus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.3.75 additional information Homo sapiens PHOSPHO1 may be involved in the mineralization process ?
-
 ?
3.1.3.75 additional information Gallus gallus PHOSPHO1 may be involved in the mineralization process, plays a role in bone and cartilage matrix mineralization ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.3.75 Gallus gallus O73884 3 weeks old male and 17 days old embryonic chickens
-
3.1.3.75 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.3.75 recombinant PHOSPHO1 Gallus gallus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.3.75 bone from 3 weeks old male chickens, from tibia, diaphyseal cortical and trabecular bone, expression pattern, PHOSPHO1 is specifically expressed at sites of mineralization in bone and cartilage Gallus gallus
-
3.1.3.75 calvarium from 17 days old embryonic chickens, PHOSPHO1 gene expression Gallus gallus
-
3.1.3.75 cartilage from 3 weeks old male chickens, from tibia, growth plate cartilage, expression pattern, PHOSPHO1 is specifically expressed at sites of mineralization in bone and cartilage Gallus gallus
-
3.1.3.75 additional information no PHOSPHO1 gene expression in non-mineralizing MG-63 osteoblast-like cells Homo sapiens
-
3.1.3.75 additional information not in heart, liver, lung, abdominal fat, kidney, skeletal and heart muscle Gallus gallus
-
3.1.3.75 SAOS-2 cell mineralizing osteoblast-like cells, PHOSPHO1 gene expression profile Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.3.75 additional information PHOSPHO1 may be involved in the mineralization process Homo sapiens ?
-
 ?
3.1.3.75 additional information PHOSPHO1 may be involved in the mineralization process, plays a role in bone and cartilage matrix mineralization Gallus gallus ?
-
 ?

Subunits

EC Number Subunits Comment Organism
3.1.3.75 ? x * 33000, recombinant PHOSPHO1, SDS-PAGE, x * 28600, x * 30400, alternative transcripts for PHOSPHO1 in growth cartilage, Western blot analysis Gallus gallus

Synonyms

EC Number Synonyms Comment Organism
3.1.3.75 More PHOSPHO1 is a member of the haloacid dehalogenase superfamily of hydrolases Homo sapiens
3.1.3.75 More PHOSPHO1 is a member of the haloacid dehalogenase superfamily of hydrolases Gallus gallus