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Literature summary extracted from

  • Jones, M.A.; Taneja, M.; Xu, Y.; Chung, W.; Stob, C.M.; Lash, T.D.
    An effective chromatographic separation of chicken red blood cell coproporphyrinogen oxidase and uroporphyrinogen decarboxylase, two enzymes in heme biosynthesis (2004), Bioorg. Med. Chem. Lett., 14, 5559-5564.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.3.3.3 coproporphyrinogen-III + O2 Gallus gallus 6th step in heme biosynthesis, pathway overview protoporphyrinogen-IX + CO2 + H2O
-
 ?
4.1.1.37 additional information Gallus gallus the enzyme is involved in heme biosynthesis ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.3.3.3 Gallus gallus
-
-
-
4.1.1.37 Gallus gallus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.3.3.3 separation of coproporphyrinogen oxidase, EC 1.3.3.3, from uroporphyrinogen decarboxylase, EC 4.1.1.37, by coproporphyrinogen-III-resin affinity chromatography, elution in a salt gradient Gallus gallus
4.1.1.37 substrate ligand column is developed by covalently linking coproporphyrin-III to a Sepharose resin. The ligand-resin chromatography step rapidly separates coproporphyrinogen oxidase from uroporphyrinogen decarboxylase Gallus gallus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.3.3.3 erythrocyte
-
 Gallus gallus
-
4.1.1.37 erythrocyte
-
 Gallus gallus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.3.3.3 coproporphyrinogen-III + O2 6th step in heme biosynthesis, pathway overview Gallus gallus protoporphyrinogen-IX + CO2 + H2O
-
 ?
1.3.3.3 coproporphyrinogen-III + O2 conversion of 2 propionate groups to 2 vinyl groups by oxidative decarboxylation Gallus gallus protoporphyrinogen-IX + CO2 + H2O
-
 ?
4.1.1.37 additional information the enzyme is involved in heme biosynthesis Gallus gallus ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.3.3.3 copro'gen oxidase
-
 Gallus gallus