Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Tanaka, T.; Kawase, M.; Tani, S.
    alpha-Hydroxyketones as inhibitors of urease (2004), Bioorg. Med. Chem., 12, 501-505.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.5.1.5 2,2'-thenoin IC50: 0.18 mM Canavalia ensiformis
3.5.1.5 2-hydroxy-1-phenylethanone IC50: 0.47 mM Canavalia ensiformis
3.5.1.5 Acetohydroxamic acid IC50: 0.005 mM Canavalia ensiformis
3.5.1.5 acetol IC50: 2.9 mM Canavalia ensiformis
3.5.1.5 furoin IC50: 0.36 mM Canavalia ensiformis
3.5.1.5 Hydroxyurea IC50: 0.1 mM Canavalia ensiformis

Organism

EC Number Organism UniProt Comment Textmining
3.5.1.5 Canavalia ensiformis
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.5.1.5 urea + H2O
-
 Canavalia ensiformis CO2 + NH3
-
 ?

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
3.5.1.5 0.005
-
 IC50: 0.005 mM Canavalia ensiformis Acetohydroxamic acid
3.5.1.5 0.1
-
 IC50: 0.1 mM Canavalia ensiformis Hydroxyurea
3.5.1.5 0.18
-
 IC50: 0.18 mM Canavalia ensiformis 2,2'-thenoin
3.5.1.5 0.36
-
 IC50: 0.36 mM Canavalia ensiformis furoin
3.5.1.5 0.47
-
 IC50: 0.47 mM Canavalia ensiformis 2-hydroxy-1-phenylethanone
3.5.1.5 2.9
-
 IC50: 2.9 mM Canavalia ensiformis acetol