Literature summary extracted from

Yamashita, A.; Endo, M.; Higashi, T.; Nakatsu, T.; Yamada, Y.; Oda, J.; Kato, H.
Capturing enzyme structure prior to reaction initiation: tropinone reductase-II-substrate complexes (2003), Biochemistry, 42, 5566-5573.

KM Value [mM]

EC Number	KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
1.1.1.236	0.0171	-	NADPH	pH 7.5, 15°C	Datura stramonium
1.1.1.236	0.0949	-	tropinone	pH 7.5, 15°C	Datura stramonium

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.1.1.236	Datura stramonium	P50163	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.1.1.236	tropinone + NADPH + H+	one of the substrates, tropinone, is rotated relative to the en product so as to make the spatial organization in the active site favorable for the reaction to proceed	Datura stramonium	pseudotropine + NADP+	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
1.1.1.236	TR-II	-	Datura stramonium
1.1.1.236	tropinone reductase-II	-	Datura stramonium

Turnover Number [1/s]

EC Number	Turnover Number Minimum [1/s]	Turnover Number Maximum [1/s]	Substrate	Comment	Organism	Structure
1.1.1.236	71.4	-	NADPH	pH 7.5, 15°C	Datura stramonium
1.1.1.236	71.4	-	tropinone	pH 7.5, 15°C	Datura stramonium

Cofactor

EC Number	Cofactor	Comment	Organism	Structure
1.1.1.236	NADPH	-	Datura stramonium

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Release 2023.1 (January 2023)