EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
3.1.26.5 | additional information | enzyme requires low salt levels | Bacillus subtilis | |
3.1.26.5 | additional information | enzyme requires very high salt levels | Methanothermobacter thermautotrophicus |
EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
3.1.26.5 | additional information | complete deletion of the protein subunit is lethal, mutation of P3 loop causes defects in pre-tRNA processing and enzyme RPR1 RNA maturation as well as subunit interaction in vivo | Saccharomyces cerevisiae |
3.1.26.5 | additional information | mutagenesis of the CR-IV region of the enzyme RPR1 RNA results in large reduction of kcat with little effect on Km | Bacillus subtilis |
3.1.26.5 | additional information | mutagenesis of the CR-IV region of the enzyme RPR1 RNA results in large reduction of kcat with little effect on Km | Escherichia coli |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.1.26.5 | additional information | substitution of the pro-Rp nonbridging oxygen with sulfur at the scissile bond does not inhibit the enzyme | Spinacia oleracea |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.1.26.5 | additional information | - |
additional information | kinetics | Saccharomyces cerevisiae | |
3.1.26.5 | additional information | - |
additional information | kinetics, the rate constant for the scissile bond cleavage is pH-dependent | Bacillus subtilis | |
3.1.26.5 | 0.000009 | - |
pre-tRNATyr | - |
Saccharomyces cerevisiae | |
3.1.26.5 | 0.000016 | - |
pre-tRNA | - |
Spinacia oleracea |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
3.1.26.5 | chloroplast | - |
Cyanophora paradoxa | 9507 | - |
3.1.26.5 | chloroplast | - |
Spinacia oleracea | 9507 | - |
3.1.26.5 | chloroplast | - |
Nicotiana tabacum | 9507 | - |
3.1.26.5 | mitochondrion | - |
Cyanophora paradoxa | 5739 | - |
3.1.26.5 | mitochondrion | RNases P and MRP | Homo sapiens | 5739 | - |
3.1.26.5 | mitochondrion | RNases P and MRP, enzyme consists of RNA component Rpm1r and protein component Rpm2p, the latter is required for the processing of the first | Saccharomyces cerevisiae | 5739 | - |
3.1.26.5 | nucleolus | RNase MRP | Homo sapiens | 5730 | - |
3.1.26.5 | nucleolus | RNase MRP | Saccharomyces cerevisiae | 5730 | - |
3.1.26.5 | nucleus | - |
Cyanophora paradoxa | 5634 | - |
3.1.26.5 | nucleus | RNase P | Homo sapiens | 5634 | - |
3.1.26.5 | nucleus | RNase P | Saccharomyces cerevisiae | 5634 | - |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
3.1.26.5 | Mg2+ | preferred metal ion, absolutely required | Cyanophora paradoxa | |
3.1.26.5 | Mg2+ | preferred metal ion, absolutely required | Bacillus subtilis | |
3.1.26.5 | Mg2+ | preferred metal ion, absolutely required | Escherichia coli | |
3.1.26.5 | Mg2+ | preferred metal ion, absolutely required | Homo sapiens | |
3.1.26.5 | Mg2+ | preferred metal ion, absolutely required | Saccharomyces cerevisiae | |
3.1.26.5 | Mg2+ | preferred metal ion, absolutely required | Methanothermobacter thermautotrophicus | |
3.1.26.5 | additional information | divalent metal ions are important cofactors for the catalytic reaction and for substrate binding at the conserved loops CR-II and CR-III in proximity to the substrate aminoacyl stem | Escherichia coli | |
3.1.26.5 | additional information | divalent metal ions are important cofactors for the catalytic reaction and for substrate binding at the conserved loops CR-II and CR-III in proximity to the substrate aminoacyl stem, enhancement of substrate affinity by 1000fold | Bacillus subtilis | |
3.1.26.5 | additional information | divalent metal ions are important cofactors for the reaction | Cyanophora paradoxa | |
3.1.26.5 | additional information | divalent metal ions are important cofactors for the reaction | Homo sapiens | |
3.1.26.5 | additional information | divalent metal ions are important cofactors for the reaction | Saccharomyces cerevisiae | |
3.1.26.5 | additional information | divalent metal ions are important cofactors for the reaction | Methanothermobacter thermautotrophicus |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
3.1.26.5 | 15500 | - |
1 * 120000, RNA subunit, + 1 * 100500, protein subunit Pop1p, + 1 * 22600, protein subunit Pop3p, 1 * 32900, protein subunit Pop4p, + 1 * 19600, protein subunit Pop5p, + 1 * 18200, protein subunit Pop6p, + 1 * 15800, protein subunit Pop7p, + 1 * 15500, protein subunit Pop8p, + 1 * 32200, protein subunit Rpp1p, + 1 * 16300, protein subunit Rpr2p, or 1 * 112000, RNA subunit NME1, + 1 * 22500, protein subunit SNM1 | Saccharomyces cerevisiae |
3.1.26.5 | 15800 | - |
1 * 120000, RNA subunit, + 1 * 100500, protein subunit Pop1p, + 1 * 22600, protein subunit Pop3p, 1 * 32900, protein subunit Pop4p, + 1 * 19600, protein subunit Pop5p, + 1 * 18200, protein subunit Pop6p, + 1 * 15800, protein subunit Pop7p, + 1 * 15500, protein subunit Pop8p, + 1 * 32200, protein subunit Rpp1p, + 1 * 16300, protein subunit Rpr2p, or 1 * 112000, RNA subunit NME1, + 1 * 22500, protein subunit SNM1 | Saccharomyces cerevisiae |
3.1.26.5 | 16300 | - |
1 * 120000, RNA subunit, + 1 * 100500, protein subunit Pop1p, + 1 * 22600, protein subunit Pop3p, 1 * 32900, protein subunit Pop4p, + 1 * 19600, protein subunit Pop5p, + 1 * 18200, protein subunit Pop6p, + 1 * 15800, protein subunit Pop7p, + 1 * 15500, protein subunit Pop8p, + 1 * 32200, protein subunit Rpp1p, + 1 * 16300, protein subunit Rpr2p, or 1 * 112000, RNA subunit NME1, + 1 * 22500, protein subunit SNM1 | Saccharomyces cerevisiae |
3.1.26.5 | 18200 | - |
1 * 120000, RNA subunit, + 1 * 100500, protein subunit Pop1p, + 1 * 22600, protein subunit Pop3p, 1 * 32900, protein subunit Pop4p, + 1 * 19600, protein subunit Pop5p, + 1 * 18200, protein subunit Pop6p, + 1 * 15800, protein subunit Pop7p, + 1 * 15500, protein subunit Pop8p, + 1 * 32200, protein subunit Rpp1p, + 1 * 16300, protein subunit Rpr2p, or 1 * 112000, RNA subunit NME1, + 1 * 22500, protein subunit SNM1 | Saccharomyces cerevisiae |
3.1.26.5 | 19600 | - |
1 * 120000, RNA subunit, + 1 * 100500, protein subunit Pop1p, + 1 * 22600, protein subunit Pop3p, 1 * 32900, protein subunit Pop4p, + 1 * 19600, protein subunit Pop5p, + 1 * 18200, protein subunit Pop6p, + 1 * 15800, protein subunit Pop7p, + 1 * 15500, protein subunit Pop8p, + 1 * 32200, protein subunit Rpp1p, + 1 * 16300, protein subunit Rpr2p, or 1 * 112000, RNA subunit NME1, + 1 * 22500, protein subunit SNM1 | Saccharomyces cerevisiae |
3.1.26.5 | 22500 | - |
1 * 120000, RNA subunit, + 1 * 100500, protein subunit Pop1p, + 1 * 22600, protein subunit Pop3p, 1 * 32900, protein subunit Pop4p, + 1 * 19600, protein subunit Pop5p, + 1 * 18200, protein subunit Pop6p, + 1 * 15800, protein subunit Pop7p, + 1 * 15500, protein subunit Pop8p, + 1 * 32200, protein subunit Rpp1p, + 1 * 16300, protein subunit Rpr2p, or 1 * 112000, RNA subunit NME1, + 1 * 22500, protein subunit SNM1 | Saccharomyces cerevisiae |
3.1.26.5 | 22600 | - |
1 * 120000, RNA subunit, + 1 * 100500, protein subunit Pop1p, + 1 * 22600, protein subunit Pop3p, 1 * 32900, protein subunit Pop4p, + 1 * 19600, protein subunit Pop5p, + 1 * 18200, protein subunit Pop6p, + 1 * 15800, protein subunit Pop7p, + 1 * 15500, protein subunit Pop8p, + 1 * 32200, protein subunit Rpp1p, + 1 * 16300, protein subunit Rpr2p, or 1 * 112000, RNA subunit NME1, + 1 * 22500, protein subunit SNM1 | Saccharomyces cerevisiae |
3.1.26.5 | 32200 | - |
1 * 120000, RNA subunit, + 1 * 100500, protein subunit Pop1p, + 1 * 22600, protein subunit Pop3p, 1 * 32900, protein subunit Pop4p, + 1 * 19600, protein subunit Pop5p, + 1 * 18200, protein subunit Pop6p, + 1 * 15800, protein subunit Pop7p, + 1 * 15500, protein subunit Pop8p, + 1 * 32200, protein subunit Rpp1p, + 1 * 16300, protein subunit Rpr2p, or 1 * 112000, RNA subunit NME1, + 1 * 22500, protein subunit SNM1 | Saccharomyces cerevisiae |
3.1.26.5 | 32900 | - |
1 * 120000, RNA subunit, + 1 * 100500, protein subunit Pop1p, + 1 * 22600, protein subunit Pop3p, 1 * 32900, protein subunit Pop4p, + 1 * 19600, protein subunit Pop5p, + 1 * 18200, protein subunit Pop6p, + 1 * 15800, protein subunit Pop7p, + 1 * 15500, protein subunit Pop8p, + 1 * 32200, protein subunit Rpp1p, + 1 * 16300, protein subunit Rpr2p, or 1 * 112000, RNA subunit NME1, + 1 * 22500, protein subunit SNM1 | Saccharomyces cerevisiae |
3.1.26.5 | 100500 | - |
1 * 120000, RNA subunit, + 1 * 100500, protein subunit Pop1p, + 1 * 22600, protein subunit Pop3p, 1 * 32900, protein subunit Pop4p, + 1 * 19600, protein subunit Pop5p, + 1 * 18200, protein subunit Pop6p, + 1 * 15800, protein subunit Pop7p, + 1 * 15500, protein subunit Pop8p, + 1 * 32200, protein subunit Rpp1p, + 1 * 16300, protein subunit Rpr2p, or 1 * 112000, RNA subunit NME1, + 1 * 22500, protein subunit SNM1 | Saccharomyces cerevisiae |
3.1.26.5 | 112000 | - |
1 * 120000, RNA subunit, + 1 * 100500, protein subunit Pop1p, + 1 * 22600, protein subunit Pop3p, 1 * 32900, protein subunit Pop4p, + 1 * 19600, protein subunit Pop5p, + 1 * 18200, protein subunit Pop6p, + 1 * 15800, protein subunit Pop7p, + 1 * 15500, protein subunit Pop8p, + 1 * 32200, protein subunit Rpp1p, + 1 * 16300, protein subunit Rpr2p, or 1 * 112000, RNA subunit NME1, + 1 * 22500, protein subunit SNM1 | Saccharomyces cerevisiae |
3.1.26.5 | 120000 | - |
1 * 120000, RNA subunit, + 1 * 100500, protein subunit Pop1p, + 1 * 22600, protein subunit Pop3p, 1 * 32900, protein subunit Pop4p, + 1 * 19600, protein subunit Pop5p, + 1 * 18200, protein subunit Pop6p, + 1 * 15800, protein subunit Pop7p, + 1 * 15500, protein subunit Pop8p, + 1 * 32200, protein subunit Rpp1p, + 1 * 16300, protein subunit Rpr2p, or 1 * 112000, RNA subunit NME1, + 1 * 22500, protein subunit SNM1 | Saccharomyces cerevisiae |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.26.5 | additional information | Homo sapiens | coordination of RNA pathways, overview | ? | - |
? | |
3.1.26.5 | additional information | Saccharomyces cerevisiae | coordination of RNA pathways, overview | ? | - |
? | |
3.1.26.5 | pre-rRNA + H2O | Homo sapiens | enzyme RNase MRP plays an important role in pre-rRNA processing | mature rRNA | - |
? | |
3.1.26.5 | pre-rRNA + H2O | Saccharomyces cerevisiae | enzyme RNase MRP plays an important role in pre-rRNA processing | mature rRNA | - |
? | |
3.1.26.5 | tRNA precursor + H2O | Cyanophora paradoxa | essential enzymes in the biogenesis of tRNA, maturation | mature tRNA + 5'-oligonucleotide | - |
? | |
3.1.26.5 | tRNA precursor + H2O | Bacillus subtilis | essential enzymes in the biogenesis of tRNA, maturation | mature tRNA + 5'-oligonucleotide | - |
? | |
3.1.26.5 | tRNA precursor + H2O | Escherichia coli | essential enzymes in the biogenesis of tRNA, maturation | mature tRNA + 5'-oligonucleotide | - |
? | |
3.1.26.5 | tRNA precursor + H2O | Homo sapiens | essential enzymes in the biogenesis of tRNA, maturation | mature tRNA + 5'-oligonucleotide | - |
? | |
3.1.26.5 | tRNA precursor + H2O | Saccharomyces cerevisiae | essential enzymes in the biogenesis of tRNA, maturation | mature tRNA + 5'-oligonucleotide | - |
? | |
3.1.26.5 | tRNA precursor + H2O | Methanothermobacter thermautotrophicus | essential enzymes in the biogenesis of tRNA, maturation | mature tRNA + 5'-oligonucleotide | - |
? | |
3.1.26.5 | tRNA precursor + H2O | Spinacia oleracea | essential enzymes in the biogenesis of tRNA, maturation | mature tRNA + 5'-oligonucleotide | - |
? | |
3.1.26.5 | tRNA precursor + H2O | Nicotiana tabacum | essential enzymes in the biogenesis of tRNA, maturation | mature tRNA + 5'-oligonucleotide | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.1.26.5 | Bacillus subtilis | - |
- |
- |
3.1.26.5 | Cyanophora paradoxa | - |
- |
- |
3.1.26.5 | Escherichia coli | - |
- |
- |
3.1.26.5 | Homo sapiens | - |
- |
- |
3.1.26.5 | Methanothermobacter thermautotrophicus | - |
- |
- |
3.1.26.5 | Nicotiana tabacum | - |
- |
- |
3.1.26.5 | Saccharomyces cerevisiae | - |
- |
- |
3.1.26.5 | Spinacia oleracea | - |
- |
- |
EC Number | Posttranslational Modification | Comment | Organism |
---|---|---|---|
3.1.26.5 | no ribonucleoprotein | - |
Spinacia oleracea |
3.1.26.5 | ribonucleoprotein | - |
Cyanophora paradoxa |
3.1.26.5 | ribonucleoprotein | - |
Bacillus subtilis |
3.1.26.5 | ribonucleoprotein | - |
Escherichia coli |
3.1.26.5 | ribonucleoprotein | - |
Homo sapiens |
3.1.26.5 | ribonucleoprotein | - |
Saccharomyces cerevisiae |
3.1.26.5 | ribonucleoprotein | - |
Methanothermobacter thermautotrophicus |
3.1.26.5 | ribonucleoprotein | - |
Nicotiana tabacum |
EC Number | Purification (Comment) | Organism |
---|---|---|
3.1.26.5 | - |
Methanothermobacter thermautotrophicus |
3.1.26.5 | mitochondrial enzyme, and RNase P partially | Homo sapiens |
3.1.26.5 | nuclear enzyme | Saccharomyces cerevisiae |
EC Number | Reaction | Comment | Organism | Reaction ID |
---|---|---|---|---|
3.1.26.5 | endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor | an RNA-containing enzyme, essential for tRNA processing, generates 5'-termini or mature tRNA molecules, tRNA precursor substrate recognition and cleavage mechanism | Cyanophora paradoxa | |
3.1.26.5 | endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor | an RNA-containing enzyme, essential for tRNA processing, generates 5'-termini or mature tRNA molecules, tRNA precursor substrate recognition and cleavage mechanism | Homo sapiens | |
3.1.26.5 | endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor | an RNA-containing enzyme, essential for tRNA processing, generates 5'-termini or mature tRNA molecules, tRNA precursor substrate recognition and cleavage mechanism | Methanothermobacter thermautotrophicus | |
3.1.26.5 | endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor | an RNA-containing enzyme, essential for tRNA processing, generates 5'-termini or mature tRNA molecules, tRNA precursor substrate recognition and cleavage mechanism | Spinacia oleracea | |
3.1.26.5 | endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor | an RNA-containing enzyme, essential for tRNA processing, generates 5'-termini or mature tRNA molecules, tRNA precursor substrate recognition and cleavage mechanism | Nicotiana tabacum | |
3.1.26.5 | endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor | an RNA-containing enzyme, essential for tRNA processing, generates 5'-termini or mature tRNA molecules, tRNA precursor substrate recognition and cleavage mechanism, CR-IV region is imporatnt for tRNA binding | Bacillus subtilis | |
3.1.26.5 | endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor | an RNA-containing enzyme, essential for tRNA processing, generates 5'-termini or mature tRNA molecules, tRNA precursor substrate recognition and cleavage mechanism, CR-IV region is important for tRNA binding | Escherichia coli | |
3.1.26.5 | endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor | an RNA-containing enzyme, essential for tRNA processing, generates 5'-termini or mature tRNA molecules, tRNA precursor substrate recognition and cleavage mechanism, structure-function relationship of the RNA subunit | Saccharomyces cerevisiae |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.1.26.5 | HeLa cell | - |
Homo sapiens | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.26.5 | deproteinized pre-rRNA + H2O | large number of discrete cleavage sites | Saccharomyces cerevisiae | mature deproteinized rRNA + 5'-oligonucleotide | - |
? | |
3.1.26.5 | additional information | coordination of RNA pathways, overview | Homo sapiens | ? | - |
? | |
3.1.26.5 | additional information | coordination of RNA pathways, overview | Saccharomyces cerevisiae | ? | - |
? | |
3.1.26.5 | additional information | the recombinant holoenzyme and the Rpp20p subunit display ATPase activity | Homo sapiens | ? | - |
? | |
3.1.26.5 | pre-rRNA + H2O | enzyme RNase MRP plays an important role in pre-rRNA processing | Homo sapiens | mature rRNA | - |
? | |
3.1.26.5 | pre-rRNA + H2O | enzyme RNase MRP plays an important role in pre-rRNA processing | Saccharomyces cerevisiae | mature rRNA | - |
? | |
3.1.26.5 | pre-rRNA + H2O | RNase MRP | Saccharomyces cerevisiae | mature rRNA | - |
? | |
3.1.26.5 | pre-rRNA + H2O | RNase MRP | Homo sapiens | mature rRNA + 5'-oligonucleotide | - |
? | |
3.1.26.5 | pre-tRNA + H2O | - |
Spinacia oleracea | mature tRNA + 5'-oligonucleotide | - |
? | |
3.1.26.5 | tRNA precursor + H2O | essential enzymes in the biogenesis of tRNA, maturation | Cyanophora paradoxa | mature tRNA + 5'-oligonucleotide | - |
? | |
3.1.26.5 | tRNA precursor + H2O | essential enzymes in the biogenesis of tRNA, maturation | Bacillus subtilis | mature tRNA + 5'-oligonucleotide | - |
? | |
3.1.26.5 | tRNA precursor + H2O | essential enzymes in the biogenesis of tRNA, maturation | Escherichia coli | mature tRNA + 5'-oligonucleotide | - |
? | |
3.1.26.5 | tRNA precursor + H2O | essential enzymes in the biogenesis of tRNA, maturation | Homo sapiens | mature tRNA + 5'-oligonucleotide | - |
? | |
3.1.26.5 | tRNA precursor + H2O | essential enzymes in the biogenesis of tRNA, maturation | Saccharomyces cerevisiae | mature tRNA + 5'-oligonucleotide | - |
? | |
3.1.26.5 | tRNA precursor + H2O | essential enzymes in the biogenesis of tRNA, maturation | Methanothermobacter thermautotrophicus | mature tRNA + 5'-oligonucleotide | - |
? | |
3.1.26.5 | tRNA precursor + H2O | essential enzymes in the biogenesis of tRNA, maturation | Spinacia oleracea | mature tRNA + 5'-oligonucleotide | - |
? | |
3.1.26.5 | tRNA precursor + H2O | essential enzymes in the biogenesis of tRNA, maturation | Nicotiana tabacum | mature tRNA + 5'-oligonucleotide | - |
? | |
3.1.26.5 | tRNA precursor + H2O | cleavage of 5'-terminal oligonucleotide | Cyanophora paradoxa | mature tRNA + 5'-oligonucleotide | generates 5'-phosphate,3'-hydroxyl-product | ? | |
3.1.26.5 | tRNA precursor + H2O | cleavage of 5'-terminal oligonucleotide | Bacillus subtilis | mature tRNA + 5'-oligonucleotide | generates 5'-phosphate,3'-hydroxyl-product | ? | |
3.1.26.5 | tRNA precursor + H2O | cleavage of 5'-terminal oligonucleotide | Escherichia coli | mature tRNA + 5'-oligonucleotide | generates 5'-phosphate,3'-hydroxyl-product | ? | |
3.1.26.5 | tRNA precursor + H2O | cleavage of 5'-terminal oligonucleotide | Homo sapiens | mature tRNA + 5'-oligonucleotide | generates 5'-phosphate,3'-hydroxyl-product | ? | |
3.1.26.5 | tRNA precursor + H2O | cleavage of 5'-terminal oligonucleotide | Saccharomyces cerevisiae | mature tRNA + 5'-oligonucleotide | generates 5'-phosphate,3'-hydroxyl-product | ? | |
3.1.26.5 | tRNA precursor + H2O | cleavage of 5'-terminal oligonucleotide | Methanothermobacter thermautotrophicus | mature tRNA + 5'-oligonucleotide | generates 5'-phosphate,3'-hydroxyl-product | ? | |
3.1.26.5 | tRNA precursor + H2O | cleavage of 5'-terminal oligonucleotide | Spinacia oleracea | mature tRNA + 5'-oligonucleotide | generates 5'-phosphate,3'-hydroxyl-product | ? | |
3.1.26.5 | tRNA precursor + H2O | cleavage of 5'-terminal oligonucleotide | Nicotiana tabacum | mature tRNA + 5'-oligonucleotide | generates 5'-phosphate,3'-hydroxyl-product | ? | |
3.1.26.5 | tRNATyr precursor + H2O | cleavage of 5'-terminal oligonucleotide | Saccharomyces cerevisiae | mature tRNATyr + 5'-oligonucleotide | generates 5'-phosphate,3'-hydroxyl-product | ? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
3.1.26.5 | decamer | 1 * 120000, RNA subunit, + 1 * 100500, protein subunit Pop1p, + 1 * 22600, protein subunit Pop3p, 1 * 32900, protein subunit Pop4p, + 1 * 19600, protein subunit Pop5p, + 1 * 18200, protein subunit Pop6p, + 1 * 15800, protein subunit Pop7p, + 1 * 15500, protein subunit Pop8p, + 1 * 32200, protein subunit Rpp1p, + 1 * 16300, protein subunit Rpr2p, or 1 * 112000, RNA subunit NME1, + 1 * 22500, protein subunit SNM1 | Saccharomyces cerevisiae |
3.1.26.5 | More | subunit composition, 1 essential RNA subunit | Cyanophora paradoxa |
3.1.26.5 | More | subunit composition, 1 large RNA subunit plus 1 small protein subunit contributing to about 10% of the mass of the holoenzyme | Bacillus subtilis |
3.1.26.5 | More | subunit composition, 1 large RNA subunit plus 1 small protein subunit contributing to about 10% of the mass of the holoenzyme | Escherichia coli |
3.1.26.5 | More | subunit composition, at least 4 protein subunits namely MTH11, MTH687, MTH688, and MTH1618 | Methanothermobacter thermautotrophicus |
3.1.26.5 | More | subunit interactions, subunit composition for RNase P: 1 RNA subunit RPM1 plus at least 1 protein subunit Rpm2p for the mitochondrial ribozyme, 9 protein components for the nuclear enzyme form, namely Pop1p, Pop3p-Pop8p, Rpp1p, and Rpr2p, secondary structure of nuclear enzyme RNA, subunit composition for RNase MRP: 1 RNA subunit NME1 plus 9 protein components for the nuclear enzyme form, namely Pop1p, Pop3p-Pop7p, Pop, Rpp1p, and SNM1, overview, Pop7p is also known as Rpp2p, structure-function relationship of the RNA subunit | Saccharomyces cerevisiae |
3.1.26.5 | oligomer | subunit composition and interaction, 1 essential RNA subunit, i.e. H1 for RNase P or 7-2 for RNase MRP, plus 9 protein components namely Pop1p, Rpp29p, Rpp20p, Rpp30p, Rep38p, Rpp40p, Rpp25p, and Rpp14p for RNase P, or pls 4 protein components namely Pop1p, Rpp29p, Rpp20p, and Rpp30p for RNase MRP, overview | Homo sapiens |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.1.26.5 | RNase MRP | - |
Homo sapiens |
3.1.26.5 | RNase MRP | - |
Saccharomyces cerevisiae |
3.1.26.5 | RNase P | - |
Cyanophora paradoxa |
3.1.26.5 | RNase P | - |
Bacillus subtilis |
3.1.26.5 | RNase P | - |
Escherichia coli |
3.1.26.5 | RNase P | - |
Homo sapiens |
3.1.26.5 | RNase P | - |
Saccharomyces cerevisiae |
3.1.26.5 | RNase P | - |
Methanothermobacter thermautotrophicus |
3.1.26.5 | RNase P | - |
Spinacia oleracea |
3.1.26.5 | RNase P | - |
Nicotiana tabacum |
EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.1.26.5 | 1.3 | - |
pre-tRNATyr | - |
Saccharomyces cerevisiae | |
3.1.26.5 | 6 | - |
tRNA precursor | enzyme RNA moiety, pH 7.0 | Bacillus subtilis |
EC Number | Organism | Comment | pI Value Maximum | pI Value |
---|---|---|---|---|
3.1.26.5 | Saccharomyces cerevisiae | protein subunits Pop1p, Pop3p, Pop4p, Pop6p, Pop7p, Rpp1p, and Rpr2p | 4.7 | 4.6 |
3.1.26.5 | Saccharomyces cerevisiae | protein subunit Pop8p | - |
4.9 |
3.1.26.5 | Saccharomyces cerevisiae | protein subunit Pop5p | - |
6.9 |