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Literature summary extracted from

  • Griengl, H.; Schwab, H.; Fechter, M.
    The synthesis of chiral cyanohydrins by oxynitrilases (2000), Trends Biotechnol., 18, 252-256.
    View publication on PubMed

Application

EC Number Application Comment Organism
4.1.2.47 agriculture enantiomerically pure cyanohydrins produced by enzyme-catalyzed synthesis are important synthetic intermediates for agrochemicals Hevea brasiliensis
4.1.2.47 agriculture enantiomerically pure cyanohydrins produced by enzyme-catalyzed synthesis are important synthetic intermediates for agrochemicals Manihot esculenta
4.1.2.47 pharmacology enantiomerically pure cyanohydrins produced by enzyme-catalyzed synthesis are important synthetic intermediates for pharmaceuticals Hevea brasiliensis
4.1.2.47 pharmacology enantiomerically pure cyanohydrins produced by enzyme-catalyzed synthesis are important synthetic intermediates for pharmaceuticals Manihot esculenta

Cloned(Commentary)

EC Number Cloned (Comment) Organism
4.1.2.47 full-length cDNA functinal expressed in Escherichia coli, Pichia pastoris and Saccharomyces cerevisiae Hevea brasiliensis

Organism

EC Number Organism UniProt Comment Textmining
4.1.2.47 Hevea brasiliensis
-
-
-
4.1.2.47 Manihot esculenta
-
 cassava, Crantz
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.2.47 HCN + (2E)-oct-2-enal
-
 Hevea brasiliensis (2S,3E)-2-hydroxynon-3-enenitrile
-
 ?
4.1.2.47 HCN + 3-furaldehyde
-
 Manihot esculenta (2R)-3-furyl(hydroxy)acetonitrile
-
 ?
4.1.2.47 HCN + 3-phenoxybenzaldehyde
-
 Hevea brasiliensis (2S)-hydroxy(3-phenoxyphenyl)acetonitrile
-
 ?
4.1.2.47 HCN + cyclohexanecarbaldehyde
-
 Hevea brasiliensis (2R)-cyclohexyl(hydroxy)acetonitrile
-
 ?
4.1.2.47 HCN + phenylacetaldehyde
-
 Hevea brasiliensis (2R)-2-hydroxy-3-phenylpropanenitrile
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.1.2.47 alpha-Hydroxynitrile lyase
-
 Manihot esculenta
4.1.2.47 HNL
-
 Hevea brasiliensis
4.1.2.47 HNL
-
 Manihot esculenta
4.1.2.47 Hydroxynitrile lyase
-
 Hevea brasiliensis
4.1.2.47 Hydroxynitrile lyase
-
 Manihot esculenta
4.1.2.47 Oxynitrilase
-
 Hevea brasiliensis
4.1.2.47 Oxynitrilase
-
 Manihot esculenta