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Literature summary extracted from

  • Cvirn, G.; Gallistl, S.; Koestenberger, M.; Kutschera, J.; Leschnik, B.; Muntean, W.
    Alpha 2-macroglobulin enhances prothrombin activation and thrombin potential by inhibiting the anticoagulant protein C/protein S system in cord and adult plasma (2002), Thromb. Res., 105, 433-439.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.21.69 alpha-2-Macroglobulin
-
 Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.4.21.69 Homo sapiens
-
 human
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.21.69 factor V + H2O
-
 Homo sapiens ?
-
 ?
3.4.21.69 factor VIII + H2O
-
 Homo sapiens ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.21.69 anticoagulant protein C/protein S system
-
 Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
3.4.21.69 protein S vitamin K-dependent plasma protein serves as cofactor for the anticoagulant activities of activated protein C Homo sapiens