EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.1.4.53 | cGMP | 5% inhibition at 0.1 mM | Homo sapiens | |
3.1.4.53 | erythro-9-(2-hydroxy-3-nonyl)adenine | 7.4% inhibition at 0.1 mM | Homo sapiens | |
3.1.4.53 | Milrinone | 42% inhibition at 0.1 mM | Homo sapiens | |
3.1.4.53 | rolipram | 18% inhibition at 0.1 mM | Homo sapiens | |
3.1.4.53 | zaprinast | 10% inhibition at 0.05 mM | Homo sapiens |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.1.4.53 | 0.0001 | - |
cAMP | - |
Homo sapiens |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
3.1.4.53 | 38800 | - |
x * 39000, SDS-PAGE, x * 38800, deduced from gene sequence, both N-terminally truncated enzyme | Homo sapiens |
3.1.4.53 | 39000 | - |
x * 39000, SDS-PAGE, x * 38800, deduced from gene sequence, both N-terminally truncated enzyme | Homo sapiens |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.1.4.53 | Homo sapiens | - |
PDE7A, recombinant protein, N-terminally truncated | - |
EC Number | Purification (Comment) | Organism |
---|---|---|
3.1.4.53 | from inclusion bodies | Homo sapiens |
EC Number | Renatured (Comment) | Organism |
---|---|---|
3.1.4.53 | refolding to active enzyme from inclusion bodies requires high concentrations of arginine hydrochloride, ethylene glycol, and magnesium chloride at pH 8.5 | Homo sapiens |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.4.53 | cAMP + H2O | - |
Homo sapiens | AMP | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
3.1.4.53 | ? | x * 39000, SDS-PAGE, x * 38800, deduced from gene sequence, both N-terminally truncated enzyme | Homo sapiens |
EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.1.4.53 | 0.3 | - |
cAMP | - |
Homo sapiens |