BRENDA - Enzyme Database show

Stereochemistry and mechanism of the conversion of 5-aminolaevulinic acid into porphobilinogen catalysed by porphobilinogen synthase

Goodwin, C.E.; Leeper, F.J.; Org. Biomol. Chem. 1, 1443-1446 (2003)

Data extracted from this reference:

Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
4.2.1.24
Bacillus subtilis
-
-
-
4.2.1.24
Bos taurus
-
-
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
4.2.1.24
liver
-
Bos taurus
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
4.2.1.24
5-aminolevulinate + 5-aminolevulinate
(3R)-5-aminolevulinate shows a significantly larger isotope effect than (3S)-5-aminolevulinate
653399
Bacillus subtilis
porphobilinogen + 2 H2O
-
653399
Bacillus subtilis
?
4.2.1.24
5-aminolevulinate + 5-aminolevulinate
(3R)-5-aminolevulinate shows a significantly larger isotope effect than (3S)-5-aminolevulinate
653399
Bos taurus
porphobilinogen + 2 H2O
-
653399
Bos taurus
?
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
4.2.1.24
liver
-
Bos taurus
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
4.2.1.24
5-aminolevulinate + 5-aminolevulinate
(3R)-5-aminolevulinate shows a significantly larger isotope effect than (3S)-5-aminolevulinate
653399
Bacillus subtilis
porphobilinogen + 2 H2O
-
653399
Bacillus subtilis
?
4.2.1.24
5-aminolevulinate + 5-aminolevulinate
(3R)-5-aminolevulinate shows a significantly larger isotope effect than (3S)-5-aminolevulinate
653399
Bos taurus
porphobilinogen + 2 H2O
-
653399
Bos taurus
?