EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.1.1.7 | bambuterol | 50% inhibition at 0.03 mM | Homo sapiens | |
3.1.1.7 | bisnorcymserine | 50% inhibition at mM | Homo sapiens | |
3.1.1.7 | cymserine | inhibition in the nanomolar range | Homo sapiens | |
3.1.1.7 | donepezil | inhibition in the nanomolar range | Homo sapiens | |
3.1.1.7 | eptastigmine | inhibition in the nanomolar range | Homo sapiens | |
3.1.1.7 | ethopropazine | 50% inhibition at 0.26 mM | Homo sapiens | |
3.1.1.7 | galantamine | inhibition in the nanomolar range | Homo sapiens | |
3.1.1.7 | huperzine | inhibition in the nanomolar range | Homo sapiens | |
3.1.1.7 | iso-ompa | 50% inhibition at 0.034 mM | Homo sapiens | |
3.1.1.7 | metrifonate | inhibition in the nanomolar range | Homo sapiens | |
3.1.1.7 | phenserine | inhibition in the nanomolar range | Homo sapiens | |
3.1.1.7 | phenylethylcymserine | 50% inhibition at 0.03 mM | Homo sapiens | |
3.1.1.7 | physostigmine | inhibition in the nanomolar range | Homo sapiens | |
3.1.1.7 | rivastigmine | 50% inhibition at 0.048 mM | Homo sapiens | |
3.1.1.7 | tacrine | inhibition in the nanomolar range | Homo sapiens | |
3.1.1.8 | bambuterol | inhibition in the nanomolar range | Homo sapiens | |
3.1.1.8 | bisnorcymserine | inhibition in the nanomolar range | Homo sapiens | |
3.1.1.8 | cymserine | inhibition in the nanomolar range | Homo sapiens | |
3.1.1.8 | donepezil | 50% inhibition at 0.004 mM | Homo sapiens | |
3.1.1.8 | eptastigmine | inhibition in the nanomolar range | Homo sapiens | |
3.1.1.8 | ethopropazine | inhibition in the nanomolar range | Homo sapiens | |
3.1.1.8 | galantamine | 50% inhibition at 0.0073 mM | Homo sapiens | |
3.1.1.8 | huperzine | 50% inhibition at 0.03 mM | Homo sapiens | |
3.1.1.8 | iso-ompa | inhibition in the nanomolar range | Homo sapiens | |
3.1.1.8 | metrifonate | 50% inhibition at 0.018 mM | Homo sapiens | |
3.1.1.8 | phenserine | 50% inhibition at 0.0015 mM | Homo sapiens | |
3.1.1.8 | phenylethylcymserine | inhibition in the nanomolar range | Homo sapiens | |
3.1.1.8 | physostigmine | inhibition in the nanomolar range | Homo sapiens | |
3.1.1.8 | rivastigmine | 50% inhibition at 0.054 mM | Homo sapiens | |
3.1.1.8 | tacrine | inhibition in the nanomolar range | Homo sapiens |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.1.8 | additional information | Homo sapiens | butyrylcholine is not a physiological substrate, enzyme may replace acetylcholine esterase in hydrolysing brain acetylcholine in patients with advanced stages of Alzheimer's disease | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.1.1.7 | Homo sapiens | - |
- |
- |
3.1.1.8 | Homo sapiens | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.1.1.7 | brain | - |
Homo sapiens | - |
3.1.1.8 | brain | - |
Homo sapiens | - |
3.1.1.8 | glial cell | - |
Homo sapiens | - |
3.1.1.8 | neuron | - |
Homo sapiens | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.1.7 | acetylcholine + H2O | - |
Homo sapiens | choline + acetate | - |
? | |
3.1.1.8 | acetylcholine + H2O | - |
Homo sapiens | choline + acetate | - |
? | |
3.1.1.8 | butyrylthiocholine + H2O | - |
Homo sapiens | thiocholine + butyrate | - |
? | |
3.1.1.8 | additional information | butyrylcholine is not a physiological substrate, enzyme may replace acetylcholine esterase in hydrolysing brain acetylcholine in patients with advanced stages of Alzheimer's disease | Homo sapiens | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.1.1.8 | butyrocholinesterase | - |
Homo sapiens |
3.1.1.8 | ChE-II | - |
Homo sapiens |
3.1.1.8 | serum cholinesterase | - |
Homo sapiens |