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Literature summary extracted from
- A potential fusion peptide and an integrin ligand domain in a protein active in sperm-egg fusion (1992), Nature, 356, 248-252.
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 3.4.24.B8 | DNA and amino acid sequence determination, alpha and beta subunits | Homo sapiens |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 3.4.24.B8 | plasma membrane | type I integral membrane glycoprotein, on the surface of sperm | Homo sapiens | 5886 | - |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 3.4.24.B8 | 44000 | - |
1 * 60000, alpha subunit, + 1 * 44000, beta subunit, SDS-PAGE | Homo sapiens |
| 3.4.24.B8 | 60000 | - |
1 * 60000, alpha subunit, + 1 * 44000, beta subunit, SDS-PAGE | Homo sapiens |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.24.B8 | additional information | Homo sapiens | the enzyme mediates the cell-cell membrane fusion of egg and sperm | ? | - |
? |  |
| 3.4.24.B8 | proteins + H2O | Homo sapiens | - |
peptides | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.24.B8 | Homo sapiens | - |
- |
- |
Posttranslational Modification
| EC Number | Posttranslational Modification | Comment | Organism |
|---|---|---|---|
| 3.4.24.B8 | glycoprotein | N-glycosylation | Homo sapiens |
| 3.4.24.B8 | proteolytic modification | processing of precursor to mature protein | Homo sapiens |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.4.24.B8 | - |
Homo sapiens |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.4.24.B8 | sperm | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.24.B8 | additional information | the enzyme mediates the cell-cell membrane fusion of egg and sperm | Homo sapiens | ? | - |
? | |
| 3.4.24.B8 | proteins + H2O | - |
Homo sapiens | peptides | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 3.4.24.B8 | dimer | 1 * 60000, alpha subunit, + 1 * 44000, beta subunit, SDS-PAGE | Homo sapiens |
| 3.4.24.B8 | More | the alpha subunit contains a putative fusion peptide, beta subunit contains a soluble disintegrin ligand | Homo sapiens |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.4.24.B8 | M12.201 | Merops-ID | Homo sapiens |
| 3.4.24.B8 | PH-30 | - |
Homo sapiens |
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