BRENDA - Enzyme Database

Kinetic analysis of sphingoid base inhibition of yeast phosphatidate phosphatase

Wu, W.I.; Carman, G.M.; Methods Enzymol. 312, 373-380 (2000)

Data extracted from this reference:

Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
3.1.3.4
phytosphingosine
-
Saccharomyces cerevisiae
3.1.3.4
psychosine
-
Saccharomyces cerevisiae
3.1.3.4
sphinganine
-
Saccharomyces cerevisiae
3.1.3.4
sphingosine
-
Saccharomyces cerevisiae
3.1.3.4
Stearylamine
-
Saccharomyces cerevisiae
Localization
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
3.1.3.4
membrane
two membrane-associated forms, 45000 Da and 104000 Da, of the Mg2+-dependent phosphatidate phosphatase
Saccharomyces cerevisiae
16020
-
Metals/Ions
EC Number
Metals/Ions
Commentary
Organism
Structure
3.1.3.4
Mg2+
two membrane-associated forms, 45000 Da and 104000 Da, of the Mg2+-dependent phosphatidate phosphatase
Saccharomyces cerevisiae
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
3.1.3.4
additional information
Saccharomyces cerevisiae
the enzyme plays an important role in regulating lipid synthesis in Saccharomyces cerevisiae, the enzyme is also involved in cell signaling mechanisms as part of the phospholipase D-phosphatidate phosphatase pathway
?
-
Saccharomyces cerevisiae
?
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
3.1.3.4
Saccharomyces cerevisiae
-
-
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.1.3.4
additional information
the enzyme plays an important role in regulating lipid synthesis in Saccharomyces cerevisiae, the enzyme is also involved in cell signaling mechanisms as part of the phospholipase D-phosphatidate phosphatase pathway
653123
Saccharomyces cerevisiae
?
-
653123
Saccharomyces cerevisiae
?
3.1.3.4
phosphatidate + H2O
-
653123
Saccharomyces cerevisiae
1,2-diacyl-sn-glycerol + phosphate
-
653123
Saccharomyces cerevisiae
?
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
3.1.3.4
phytosphingosine
-
Saccharomyces cerevisiae
3.1.3.4
psychosine
-
Saccharomyces cerevisiae
3.1.3.4
sphinganine
-
Saccharomyces cerevisiae
3.1.3.4
sphingosine
-
Saccharomyces cerevisiae
3.1.3.4
Stearylamine
-
Saccharomyces cerevisiae
Localization (protein specific)
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
3.1.3.4
membrane
two membrane-associated forms, 45000 Da and 104000 Da, of the Mg2+-dependent phosphatidate phosphatase
Saccharomyces cerevisiae
16020
-
Metals/Ions (protein specific)
EC Number
Metals/Ions
Commentary
Organism
Structure
3.1.3.4
Mg2+
two membrane-associated forms, 45000 Da and 104000 Da, of the Mg2+-dependent phosphatidate phosphatase
Saccharomyces cerevisiae
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
3.1.3.4
additional information
Saccharomyces cerevisiae
the enzyme plays an important role in regulating lipid synthesis in Saccharomyces cerevisiae, the enzyme is also involved in cell signaling mechanisms as part of the phospholipase D-phosphatidate phosphatase pathway
?
-
Saccharomyces cerevisiae
?
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.1.3.4
additional information
the enzyme plays an important role in regulating lipid synthesis in Saccharomyces cerevisiae, the enzyme is also involved in cell signaling mechanisms as part of the phospholipase D-phosphatidate phosphatase pathway
653123
Saccharomyces cerevisiae
?
-
653123
Saccharomyces cerevisiae
?
3.1.3.4
phosphatidate + H2O
-
653123
Saccharomyces cerevisiae
1,2-diacyl-sn-glycerol + phosphate
-
653123
Saccharomyces cerevisiae
?