Literature summary extracted from

Chung, S.J.; Chung, S.; Lee, H.S.; Kim, E.J.; Oh, K.S.; Choi, H.S.; Kim, K.S.; Kim, Y.J.; Hahn, J.H.; Kim, D.H.
Mechanistic insight into the inactivation of carboxypeptidase A by alpha-benzyl-2-oxo-1,3-oxazolidine-4-acetic acid, a novel type of irreversible inhibitor for carboxypeptidase A with no stereospecificity (2001), J. Org. Chem., 66, 6462-6471.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
3.4.17.1	alpha-benzyl-2-oxo-1,3-oxazolidine-4-acetic acid	all four stereoisomers inhibit in a time dependent manner, inhibited enzyme does not regain its enzymatic activity upon dialysis, inactivation is prevented by 2-benzylsuccinic acid	Bos taurus
3.4.17.1	alpha-benzyl-2-oxo-1,3-oxazolidine-5-acetic acid	irreversible	Bos taurus

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.4.17.1	Bos taurus	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3.4.17.1	hippuryl-L-Phe + H2O	-	Bos taurus	hippuric acid + Phe	-	?

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)