BRENDA - Enzyme Database

The crystal structure of Trypanosoma brucei enolase: visualisation of the inhibitory metal binding site III and potential as target for selective, irreversible inhibition

da Silva Giotto, M.T.; Hannaert, V.; Vertommen, D.; de, A.S.N.M.V.; Rider, M.H.; Michels, P.A.; Garratt, R.C.; Rigden, D.J.; J. Mol. Biol. 331, 653-665 (2003)

Data extracted from this reference:

Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
4.2.1.11
iodoacetamide
binds to cysteine residues
Trypanosoma brucei
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
4.2.1.11
Trypanosoma brucei
Q9NDH8
-
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
4.2.1.11
2-phospho-D-glycerate
-
652923
Trypanosoma brucei
phosphoenolpyruvate
-
652923
Trypanosoma brucei
r
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
4.2.1.11
iodoacetamide
binds to cysteine residues
Trypanosoma brucei
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
4.2.1.11
2-phospho-D-glycerate
-
652923
Trypanosoma brucei
phosphoenolpyruvate
-
652923
Trypanosoma brucei
r