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Literature summary extracted from

  • Rigden, D.J.; Walter, R.A.; Phillips, S.E.; Fothergill-Gilmore, L.A.
    Sulphate ions observed in the 2.12 A structure of a new crystal form of S. cerevisiae phosphoglycerate mutase provide insights into understanding the catalytic mechanism (1999), J. Mol. Biol., 286, 1507-1517.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
5.4.2.11 2,3-bisphosphoglycerate
-
 Saccharomyces cerevisiae

Cloned(Commentary)

EC Number Cloned (Comment) Organism
5.4.2.11 overexpression in Saccharomyces cerevisae Saccharomyces cerevisiae

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
5.4.2.11 crystal structure at 2.12 a resolution Saccharomyces cerevisiae

Protein Variants

EC Number Protein Variants Comment Organism
5.4.2.11 A60S 69% of wild-type activity Saccharomyces cerevisiae
5.4.2.11 E86Q 1% of wild-type activity Saccharomyces cerevisiae
5.4.2.11 S11A 4% of wild-type activity Saccharomyces cerevisiae

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
5.4.2.11 0.43
-
 3-phospho-D-glycerate A60S mutant Saccharomyces cerevisiae
5.4.2.11 0.47
-
 3-phospho-D-glycerate
-
 Saccharomyces cerevisiae
5.4.2.11 0.71
-
 3-phospho-D-glycerate S11A mutant Saccharomyces cerevisiae
5.4.2.11 1.1
-
 3-phospho-D-glycerate E86Q mutant Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5.4.2.11 2-phospho-D-glycerate Saccharomyces cerevisiae
-
 3-phospho-D-glycerate
-
 r

Organism

EC Number Organism UniProt Comment Textmining
5.4.2.11 Saccharomyces cerevisiae P00950
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.4.2.11 2-phospho-D-glycerate
-
 Saccharomyces cerevisiae 3-phospho-D-glycerate
-
 r

Synonyms

EC Number Synonyms Comment Organism
5.4.2.11 PGAM
-
 Saccharomyces cerevisiae

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
5.4.2.11 4.7
-
 3-phospho-D-glycerate E86Q mutant Saccharomyces cerevisiae
5.4.2.11 20
-
 3-phospho-D-glycerate S11A mutant Saccharomyces cerevisiae
5.4.2.11 370
-
 3-phospho-D-glycerate A60S mutant Saccharomyces cerevisiae
5.4.2.11 530
-
 3-phospho-D-glycerate
-
 Saccharomyces cerevisiae