Literature summary extracted from

Villa, H.; Otero Marcos, A.R.; Reguera, R.M.; Balana-Fouce, R.; Garcia-Estrada, C.; Perez-Pertejo, Y.; Tekwani, B.L.; Myler, P.J.; Stuart, K.D.; Bjornsti, M.A.; Ordonez, D.
A novel active DNA topoisomerase I in Leishmania donovani (2003), J. Biol. Chem., 278, 3521-3526.

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
5.6.2.1	DNA topoisomerase I activity is detected only when both genes LdTOP1A and LdTOP1B are coexpressed in a yeast expression system, LdTOP1A and LdTOP1B are located on different chromosomes	Leishmania donovani

Organism

EC Number	Organism	UniProt	Comment	Textmining
5.6.2.1	Leishmania donovani	Q8WQM6	LdTOP1A gene	-
5.6.2.1	Leishmania donovani	Q8WQM6	LdTOP1B gene	-

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Release 2023.1 (January 2023)