Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Benaud, C.; Oberst, M.; Hobson, J.P.; Spiegel, S.; Dickson, R.B.; Lin, C.Y.
    Sphingosine 1-phosphate, present in serum-derived lipoproteins, activates matriptase (2002), J. Biol. Chem., 277, 10539-10546.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.4.21.109 C2 ceramide 1-phosphate weaker activator than sphingosine 1-phosphate, activation at 0.000237 mM Homo sapiens
3.4.21.109 C8 ceramide 1-phosphate weaker activator than sphingosine 1-phosphate, activation at 0.001 mM Homo sapiens
3.4.21.109 dihydrosphingosine 1-phosphate weaker activator than sphingosine 1-phosphate Homo sapiens
3.4.21.109 lysophosphatidic acid weaker activator than sphingosine 1-phosphate Homo sapiens
3.4.21.109 sphingosine 1-phosphate activation at 0.00001 mg/ml, activation is dependent on Ca2+ Homo sapiens
3.4.21.109 sphingosine phosphocholine weaker activator than sphingosine 1-phosphate Homo sapiens

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.4.21.109 expression in MDA-MB-435 breast caner cells Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.4.21.109 70000
-
 non-complexed form, SDS-PAGE Homo sapiens
3.4.21.109 120000
-
 complexed form, SDS-PAGE Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.21.109 additional information Homo sapiens degrades extracellular matrix ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.21.109 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.21.109 epithelium
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.21.109 additional information degrades extracellular matrix Homo sapiens ?
-
 ?