EC Number | Cloned (Comment) | Organism |
---|---|---|
4.1.1.17 | expression in Escherichia coli | Rattus norvegicus |
EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
4.1.1.17 | C360A | 2% of wild-type activity | Rattus norvegicus |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
4.1.1.17 | 1-diethyl-2-hydroxy-2-nitroso-hydrazine | nitric oxide donor, inhibition via S-nitrosylation of Cys360 in the active site of ODC | Rattus norvegicus | |
4.1.1.17 | S-nitrosoglutathione | inhibition likely via S-transnitrosation | Rattus norvegicus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.1.1.17 | L-ornithine | Rattus norvegicus | first step in polyamine biosynthesis | putrescine + CO2 | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
4.1.1.17 | Rattus norvegicus | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
4.1.1.17 | recombinnt ODC | Rattus norvegicus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.1.1.17 | L-ornithine | - |
Rattus norvegicus | putrescine + CO2 | - |
? | |
4.1.1.17 | L-ornithine | first step in polyamine biosynthesis | Rattus norvegicus | putrescine + CO2 | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
4.1.1.17 | ODC | - |
Rattus norvegicus |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
4.1.1.17 | pyridoxal 5'-phosphate | - |
Rattus norvegicus |