EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
4.6.1.1 | HCO3- | 50 mM, 5-20fold activation in the presence of Mg2+, 3fold activation in the presence of Mn2+ | Mus musculus | |
4.6.1.1 | HCO3- | 50 mM, 5-20fold activation in the presence of Mg2+, 3fold activation in the presence of Mn2+ | Rattus norvegicus |
EC Number | Cloned (Comment) | Organism |
---|---|---|
4.6.1.1 | expression of full length and truncated sAC in HEK293 cells | Mus musculus |
4.6.1.1 | expression of full length and truncated sAC in HEK293 cells | Rattus norvegicus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
4.6.1.1 | soluble | - |
Mus musculus | - |
- |
4.6.1.1 | soluble | - |
Rattus norvegicus | - |
- |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
4.6.1.1 | Mg2+ | 5 mM, activates sAC | Mus musculus | |
4.6.1.1 | Mg2+ | 5 mM, activates sAC | Rattus norvegicus | |
4.6.1.1 | Mn2+ | 5 mM, activates sAC | Mus musculus | |
4.6.1.1 | Mn2+ | 5 mM, activates sAC | Rattus norvegicus |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
4.6.1.1 | 46000 | - |
1 * 46000, immunoblot, truncated sAC resulting from alternative splicing | Mus musculus |
4.6.1.1 | 46000 | - |
1 * 46000, immunoblot, truncated sAC resulting from alternative splicing | Rattus norvegicus |
4.6.1.1 | 49000 | - |
gel filtration, recombinant truncated sAC | Mus musculus |
4.6.1.1 | 49000 | - |
gel filtration, recombinant truncated sAC | Rattus norvegicus |
4.6.1.1 | 171000 | - |
x * 171000, immunoblot, full length sAC | Mus musculus |
4.6.1.1 | 171000 | - |
x * 171000, immunoblot, full length sAC | Rattus norvegicus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.6.1.1 | ATP | Mus musculus | - |
3',5'-cyclic AMP + diphosphate | - |
? | |
4.6.1.1 | ATP | Rattus norvegicus | - |
3',5'-cyclic AMP + diphosphate | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
4.6.1.1 | Mus musculus | - |
- |
- |
4.6.1.1 | Rattus norvegicus | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.6.1.1 | ATP | - |
Mus musculus | 3',5'-cyclic AMP + diphosphate | - |
? | |
4.6.1.1 | ATP | - |
Rattus norvegicus | 3',5'-cyclic AMP + diphosphate | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
4.6.1.1 | ? | x * 171000, immunoblot, full length sAC | Mus musculus |
4.6.1.1 | ? | x * 171000, immunoblot, full length sAC | Rattus norvegicus |
4.6.1.1 | monomer | 1 * 46000, immunoblot, truncated sAC resulting from alternative splicing | Mus musculus |
4.6.1.1 | monomer | 1 * 46000, immunoblot, truncated sAC resulting from alternative splicing | Rattus norvegicus |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
4.6.1.1 | adenylyl cyclase | - |
Mus musculus |
4.6.1.1 | adenylyl cyclase | - |
Rattus norvegicus |
4.6.1.1 | sAC | - |
Mus musculus |
4.6.1.1 | sAC | - |
Rattus norvegicus |
4.6.1.1 | soluble adenylyl cyclase | - |
Mus musculus |
4.6.1.1 | soluble adenylyl cyclase | - |
Rattus norvegicus |